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In-silico and in-vitro study reveals Ziprasidone as a potential aromatase inhibitor against breast carcinoma
A Sahu, S Ahmad, K Imtiyaz… - Scientific Reports, 2023 - nature.com
Aromatase enzyme plays a fundamental role in the development of estrogen receptors, and
due to this functionality, the enzyme has gained significant attention as a therapeutic for …
due to this functionality, the enzyme has gained significant attention as a therapeutic for …
[HTML][HTML] Computational study on potential novel anti-Ebola virus protein VP35 natural compounds
Ebola virus (EBOV) is one of the most lethal pathogens that can infect humans. The Ebola
viral protein VP35 (EBOV VP35) inhibits host IFN-α/β production by interfering with host …
viral protein VP35 (EBOV VP35) inhibits host IFN-α/β production by interfering with host …
Identification of potential Aurora kinase-C protein inhibitors: an amalgamation of energy minimization, virtual screening, prime MMGBSA and AutoDock
R Bathula, G Lanka, N Muddagoni… - Journal of …, 2020 - Taylor & Francis
Genomic instability is a trademark of cancer evolution, there is still a wide necessity to
discover safe and effective anti-cancer drugs. Aurora kinase-C protein is a member of the …
discover safe and effective anti-cancer drugs. Aurora kinase-C protein is a member of the …
[HTML][HTML] Chemical constituents from Artemisia annua and Vitex agnus-castus as new aromatase inhibitors: In-vitro and in-silico studies
Aromatase inhibitors are important in certain cancers such as breast cancer in
postmenopausal women. In this study, eight constituents from Artemisia annua L. and Vitex …
postmenopausal women. In this study, eight constituents from Artemisia annua L. and Vitex …
[HTML][HTML] Modulation of aromatase by natural compounds—A pharmacophore guided molecular modelling simulations
S Rampogu, C Park, M Son, A Baek, A Zeb… - South African Journal of …, 2019 - Elsevier
Globally, breast cancer is one of the primary reasons of death noticed in women. Despite
continuous efforts to formulate effective treatments, search to identify promising therapeutics …
continuous efforts to formulate effective treatments, search to identify promising therapeutics …
Exploring CIP2A modulators using multiple molecular modeling approaches
S Bhowmick, K Roy, A Saha - Journal of Biomolecular Structure …, 2022 - Taylor & Francis
Like other human oncoproteins, Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A)
exerts cancer promoting function through interaction with other partner proteins, such as …
exerts cancer promoting function through interaction with other partner proteins, such as …
Finding inhibitor from phytochemicals for novel target Glycosyltransferase family 62 protein in Trichophyton rubrum using insilico study
SAM Hussain, ND Elangovan, A Malik, M Khan… - 2022 - researchsquare.com
The dermatophyte Trichophyton rubrum is producing more than 70% of dermatophytosis in
human and animals. Glycosyltransferase family 62 protein in T. rubrum is potential and …
human and animals. Glycosyltransferase family 62 protein in T. rubrum is potential and …
[PDF][PDF] Computational Study on Potential Novel Anti-Ebola Virus Protein VP35 Natural Compounds. Biomedicines 2021, 9, 1796
Ebola virus (EBOV) is one of the most lethal pathogens that can infect humans. The Ebola
viral protein VP35 (EBOV VP35) inhibits host IFN-α/β production by interfering with host …
viral protein VP35 (EBOV VP35) inhibits host IFN-α/β production by interfering with host …
[PDF][PDF] Structure of Aromatase
M Azad, RN Kumavath - researchgate.net
Conclusions• Third-generation aromatase inhibitors are currently utilized as first-line therapy
for metastatic breast cancer and as neoadjuvant treatment for primary breast cancer.• Our …
for metastatic breast cancer and as neoadjuvant treatment for primary breast cancer.• Our …