In-cell structural biology aims at extracting structural information about proteins or nucleic
acids in their native, cellular environment. This emerging field holds great promise and is …

Viral capsids are often regarded as inert structural units, but in actuality they display
fascinating dynamics during different stages of their life cycle. With the advent of single …

Viruses lacking the capacity to infect mammals exhibit minimal toxicity, good
biocompatibility, and well-defined structures. As self-organized biomolecular assemblies …

We report remarkably high, up to 100-fold, signal enhancements in 19F dynamic nuclear
polarization (DNP) magic angle spinning (MAS) spectra at 14.1 T on HIV-1 capsid protein …

The host factor protein TRIM5α plays an important role in restricting the host range of HIV-1,
interfering with the integrity of the HIV-1 capsid. TRIM5 triggers an antiviral innate immune …

NMR relaxation dispersion methods provide a holistic way to observe microsecond time-
scale protein backbone motion both in solution and in the solid state. Different nuclei (1H …

Structural virology reveals the architecture underlying infection. While notably electron
microscopy images have provided an atomic view on viruses which profoundly changed our …

Abstract 19F NMR spectroscopy is an attractive and growing area of research with broad
applications in biochemistry, chemical biology, medicinal chemistry, and materials science …

Viral hepatitis is growing into an epidemic illness, and it is urgent to neutralize the main
culprit, hepatitis B virus (HBV), a small-enveloped retrotranscribing DNA virus. An intriguing …

A number of recent advances in the field of magic-angle-spinning (MAS) solid-state NMR
have enabled its application to a range of biological systems of ever increasing complexity …