Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

Highlights•Metabolomics has become a widely applied tool in drug development.•
Metabolomics plays a key role for the identification of physiological response markers.• …

Metabolomics strives to capture the entirety of the metabolites in a biological system by
comprehensive analysis, often by liquid chromatography hyphenated to mass spectrometry …

In neuroscience research, chiral metabolomics is an emerging field, in which D-amino acids
play an important role as potential biomarkers for neurological diseases. The targeted chiral …

Background Known for its strong diuretic properties, the perennial herbaceous plant
Orthosiphon stamineus Benth. is believed to preserve the kidney disease. This study …

Lurong Dabu decoction (LRDBD) is an effective traditional Chinese Korean ethnic medicine
prescription composed of eight herbs, which is used for treating asthma. However, its …

Chiral metabolomics is starting to become a well-defined research field, powered by the
recent advances in separation techniques. This review aimed to cover the most relevant …

Metabolomics and lipidomics have demonstrated increasing importance in underlying
biochemical mechanisms involved in the pathogenesis of diseases to identify novel drug …

Here, we have documented a new protocol to determine d/l-amino acids by derivatizing
amino acids via a chiral phosphinate.(RP)-l-Menthyl phenylphosphinate was able to bond …