Alzheimer's and Parkinson's disease therapies in the clinic
P Chopade, N Chopade, Z Zhao… - Bioengineering & …, 2023 - Wiley Online Library
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent
neurodegenerative diseases, affecting millions and costing billions each year in the United …
neurodegenerative diseases, affecting millions and costing billions each year in the United …
Opportunities and challenges of alpha-synuclein as a potential biomarker for Parkinson's disease and other synucleinopathies
Abstract Parkinson's disease (PD), the second most common progressive
neurodegenerative disease, develops and progresses for 10–15 years before the clinical …
neurodegenerative disease, develops and progresses for 10–15 years before the clinical …
Scalable production of extracellular vesicles and its therapeutic values: a review
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …
secreted by cells for intercellular communication. Recently, EVs have received much …
L1CAM‐associated extracellular vesicles: A systematic review of nomenclature, sources, separation, and characterization
DE Gomes, KW Witwer - Journal of Extracellular Biology, 2022 - Wiley Online Library
When released into biological fluids like blood or saliva, brain extracellular vesicles (EVs)
might provide a window into otherwise inaccessible tissue, contributing useful biomarkers of …
might provide a window into otherwise inaccessible tissue, contributing useful biomarkers of …
Dl-3-n-butylphthalide rescues dopaminergic neurons in Parkinson's disease models by inhibiting the NLRP3 inflammasome and ameliorating mitochondrial …
R Que, J Zheng, Z Chang, W Zhang, H Li, Z **e… - Frontiers in …, 2021 - frontiersin.org
Background Neuroinflammation and mitochondrial impairment play important roles in the
neuropathogenesis of Parkinson's disease (PD). The activation of NLRP3 inflammasome …
neuropathogenesis of Parkinson's disease (PD). The activation of NLRP3 inflammasome …
Extracellular vesicles derived from neural stem cells, astrocytes, and microglia as therapeutics for easing TBI-induced brain dysfunction
C Hering, AK Shetty - Stem cells translational medicine, 2023 - academic.oup.com
Extracellular vesicles (EVs) derived from neural stem cells (NSC-EVs), astrocytes (ADEVs),
and microglia (MDEVs) have neuroregenerative properties. This review discusses the …
and microglia (MDEVs) have neuroregenerative properties. This review discusses the …
Extracellular Vesicles for the Diagnosis of Parkinson's Disease: Systematic Review and Meta‐Analysis
M Xylaki, A Chopra, S Weber, M Bartl… - Movement …, 2023 - Wiley Online Library
Parkinson's disease (PD) biomarkers are needed by both clinicians and researchers (for
diagnosis, identifying study populations, and monitoring therapeutic response). Imaging …
diagnosis, identifying study populations, and monitoring therapeutic response). Imaging …
[HTML][HTML] Neural stem cells for Parkinson's disease management: Challenges, nanobased support, and prospects
Abstract Parkinson's disease (PD), characterized by loss of nigrostriatal dopaminergic
neurons, is one of the most predominant neurodegenerative diseases affecting the elderly …
neurons, is one of the most predominant neurodegenerative diseases affecting the elderly …
Exosomes: From basic research to clinical diagnostic and therapeutic applications in cancer
S Araujo-Abad, JM Berna, E Lloret-Lopez… - Cellular Oncology, 2024 - Springer
Cancer continues to pose a global threat despite potent anticancer drugs, often
accompanied by undesired side effects. To enhance patient outcomes, sophisticated …
accompanied by undesired side effects. To enhance patient outcomes, sophisticated …
Extracellular vesicles in neurodegenerative diseases: A systematic review
Introduction Extracellular vesicles (EVs) are known to have a significant role in the central
nervous system (CNS) and neurodegenerative disease. Methods PubMed, Scopus, ISI Web …
nervous system (CNS) and neurodegenerative disease. Methods PubMed, Scopus, ISI Web …