[HTML][HTML] What is a cell type and how to define it?

H Zeng - Cell, 2022 - cell.com
Cell types are the basic functional units of an organism. Cell types exhibit diverse
phenotypic properties at multiple levels, making them challenging to define, categorize, and …

Hippocampal GABAergic interneurons and memory

A Tzilivaki, JJ Tukker, N Maier, P Poirazi, RP Sammons… - Neuron, 2023 - cell.com
One of the most captivating questions in neuroscience revolves around the brain's ability to
efficiently and durably capture and store information. It must process continuous input from …

[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Z Yao, CTJ van Velthoven, M Kunst, M Zhang… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

A multimodal cell census and atlas of the mammalian primary motor cortex

Principal manuscript editors, Analysis coordination… - Nature, 2021 - nature.com
Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …

Morphological diversity of single neurons in molecularly defined cell types

H Peng, P **e, L Liu, X Kuang, Y Wang, L Qu, H Gong… - Nature, 2021 - nature.com
Dendritic and axonal morphology reflects the input and output of neurons and is a defining
feature of neuronal types,, yet our knowledge of its diversity remains limited. Here, to …

[HTML][HTML] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells

NW Gouwens, SA Sorensen, F Baftizadeh, A Budzillo… - Cell, 2020 - cell.com
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

Local connectivity and synaptic dynamics in mouse and human neocortex

L Campagnola, SC Seeman, T Chartrand, L Kim… - Science, 2022 - science.org
We present a unique, extensive, and open synaptic physiology analysis platform and
dataset. Through its application, we reveal principles that relate cell type to synaptic …

Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex

BR Lee, R Dalley, JA Miller, T Chartrand, J Close… - Science, 2023 - science.org
Human cortex transcriptomic studies have revealed a hierarchical organization of γ-
aminobutyric acid–producing (GABAergic) neurons from subclasses to a high diversity of …

Development and functional diversification of cortical interneurons

L Lim, D Mi, A Llorca, O Marín - Neuron, 2018 - cell.com
In the cerebral cortex, GABAergic interneurons have evolved as a highly heterogeneous
collection of cell types that are characterized by their unique spatial and temporal …

PV interneurons: critical regulators of E/I balance for prefrontal cortex-dependent behavior and psychiatric disorders

BR Ferguson, WJ Gao - Frontiers in neural circuits, 2018 - frontiersin.org
Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple
complex behaviors, including working memory, cognitive flexibility, attention, social …