Pain diagnosis and management would benefit from the development of objective markers
of nociception and pain. Current research addressing this issue has focused on five main …

Portable infrared pupillometers provide an objective measure of pupil size and pupillary
reflexes, which for most clinicians was previously only a visual impression. But despite the …

Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting around 1% of
the population. We previously discovered that infant siblings of children with ASD had …

Abstract Purpose of Review Patients with acute neurologic injury require a specialized
approach to critical care, particularly with regard to sedation and analgesia. This article …

BACKGROUND: Many patients in the intensive care unit are unable to communicate
verbally. Accurately predicting whether such patients will exhibit painful behaviors during …

A fundamental question in functional brain development is how the brain acquires
specialised processing optimised for its individual environment. The current study is the first …

Background Quantitative measurement of pupil change has not been assessed against the
Richmond Agitation and Sedation Scale (RASS) and spectral edge frequency (SEF) during …

Background: Patients admitted to a cardiac intensive care unit are often unconscious with
uncertain prognosis. Automated infrared pupillometry for neurological assessment in the …

Background Evaluating depth of sedation in the intensive care unit (ICU) is crucial for the
management of mechanically ventilated patients but can be challenging in some situations …

Pupillometry is a non-invasive monitoring technique, which allows dynamic pupillary
diameter measurement by an infrared camera. Pupillary diameter increases in response to …