Neuroendocrinology of bone
The past decade has witnessed significant advances in our understanding of skeletal
homeostasis and the mechanisms that mediate the loss of bone in primary and secondary …
homeostasis and the mechanisms that mediate the loss of bone in primary and secondary …
Gene–dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer's mice
High post-menopausal levels of the pituitary gonadotropin follicle-stimulating hormone
(FSH) are strongly associated with the onset of Alzheimer's disease (AD). We have shown …
(FSH) are strongly associated with the onset of Alzheimer's disease (AD). We have shown …
Hypothalamic structure and function in Alzheimer's disease and Lewy-body dementia: a systematic review and meta-analysis
Background Changes to sleep, weight, and endocrine function are common in Alzheimer's
disease (AD) and Lewy-body dementia (LBD). The cause of these is not known, but they …
disease (AD) and Lewy-body dementia (LBD). The cause of these is not known, but they …
Sex-specific associations of serum testosterone with gray matter volume and cerebral blood flow in midlife individuals at risk for Alzheimer's disease
M Nerattini, S Williams, C Andy, C Carlton, C Zarate… - PloS one, 2025 - journals.plos.org
Testosterone, an essential sex steroid hormone, influences brain health by impacting
neurophysiology and neuropathology throughout the lifespan in both genders. However …
neurophysiology and neuropathology throughout the lifespan in both genders. However …
[HTML][HTML] Transgenic Drosophila Expressing Active Human LH Receptor in the Gonads Exhibit a Decreased Fecundity: Towards a Platform to Identify New Orally …
A Mahamid, D Ben-Menahem - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: The gonadotropins luteinizing hormone (LH) and follicle-stimulating
hormone (FSH) and their receptors are major regulators of reproduction in mammals and …
hormone (FSH) and their receptors are major regulators of reproduction in mammals and …
Causal association of sex hormone-related traits with Alzheimer's disease: a multivariable and network Mendelian randomization analysis
Y Zhang, Z Sun, Y Yang, W Fu - Frontiers in Neurology, 2025 - frontiersin.org
Background Although studies have demonstrated a correlation between sex hormone-
related traits [such as sex hormone binding globulin (SHBG) and testosterone] and …
related traits [such as sex hormone binding globulin (SHBG) and testosterone] and …
Subclinical Hyperthyroidism Enhances Gonadotropin‐Lowering Effects of Metformin in Postmenopausal Women
R Krysiak, K Kowalcze… - The Journal of Clinical …, 2024 - Wiley Online Library
Metformin treatment decreases elevated concentrations of anterior pituitary hormones. The
aim of this prospective, cohort study was to investigate whether hyperthyroidism modulates …
aim of this prospective, cohort study was to investigate whether hyperthyroidism modulates …
[HTML][HTML] Gene–Dose–Dependent Reduction Fshr Expression Improves Spatial Memory Deficits in Alzheimer's Mice
Alzheimer's disease (AD) is a major progressive neurodegenerative disorder of the aging
population. High post–menopausal levels of the pituitary gonadotropin follicle–stimulating …
population. High post–menopausal levels of the pituitary gonadotropin follicle–stimulating …