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An overview of advancement of organoruthenium (II) complexes as prospective anticancer agents
The successful clinical translation of platinum drugs for cancer treatment has witnessed an
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …
upsurge in the development of metal compounds as therapeutics and diagnostics drugs …
Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
Investigation into antiproliferative activity and apoptosis mechanism of new arene Ru (ii) carbazole-based hydrazone complexes
Ruthenium complexes with bioactive ligands are becoming promising substitutes for
platinum complexes due to their precise action against various cancers. In the present study …
platinum complexes due to their precise action against various cancers. In the present study …
Synthesis and Structure of Arene Ru(II) N∧O-Chelating Complexes: In Vitro Cytotoxicity and Cancer Cell Death Mechanism
A panel of six new structurally related organometallic arene Ru (II) complexes of general
composition [(η6-benzene) Ru (L) Cl](1–3) and [(η6-p-cymene) Ru (L) Cl](4–6)(L …
composition [(η6-benzene) Ru (L) Cl](1–3) and [(η6-p-cymene) Ru (L) Cl](4–6)(L …
Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers
AMS El-Sharief, YA Ammar, A Belal… - Bioorganic …, 2019 - Elsevier
Abstract Reaction of 5-morphilinosulfonylisatin (1) with acetophenones (2a–e) afforded 3-
hydroxy-3-substituted-2-oxoindoles 3a-e, when treated with acetic acid the expected 3 …
hydroxy-3-substituted-2-oxoindoles 3a-e, when treated with acetic acid the expected 3 …
Recent advances in anticancer ruthenium Schiff base complexes
S Parveen - Applied Organometallic Chemistry, 2020 - Wiley Online Library
Nowadays in cancer treatment, both metal complexes and organic molecules are being
widely used. Current years have seen a surge of interest in the application of organometallic …
widely used. Current years have seen a surge of interest in the application of organometallic …
[HTML][HTML] Research progress on the biological activities of metal complexes bearing polycyclic aromatic hydrazones
R Liu, J Cui, T Ding, Y Liu, H Liang - Molecules, 2022 - mdpi.com
Due to the abundant and promising biological activities of aromatic hydrazones, it is of great
significance to study the biological activities of their metal complexes for the research and …
significance to study the biological activities of their metal complexes for the research and …
In vitro evaluations of biomolecular interactions, antioxidant and anticancer activities of Nickel (II) and Copper (II) complexes with 1: 2 coordination of anthracenyl …
KS Neethu, S Sivaselvam, M Theetharappan… - Inorganica Chimica …, 2021 - Elsevier
A set of nickel (II) and copper (II) complexes incorporated anthracenyl hydrazone ligands
were synthesized and characterized with the help of various spectroscopic techniques …
were synthesized and characterized with the help of various spectroscopic techniques …
Impact of biphenyl benzhydrazone-incorporated arene Ru (II) complexes on cytotoxicity and the cancer cell death mechanism
The biological efficacy of arene ruthenium complexes is currently of great interest due to the
significance of arene moieties, chelates, and metal centers in defining and controlling their …
significance of arene moieties, chelates, and metal centers in defining and controlling their …
A review of hydrazide-hydrazone metal complexes' antitumor potential
Cancer inflicts a tremendous burden on modern society, and more effective and selective
treatments need to be developed. Metallodrugs have been extensively explored as …
treatments need to be developed. Metallodrugs have been extensively explored as …