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Targeting antimicrobial drug resistance with marine natural products
The rise and spread of antimicrobial resistance represents one of the most pressing health
issues of today. Antimicrobial resistance in micro-organisms can arise due to a multiplicity of …
issues of today. Antimicrobial resistance in micro-organisms can arise due to a multiplicity of …
Nanocatalyzed synthetic approach for quinazoline and quinazolinone derivatives: A review (2015–present)
Quinazolines and their derivative are among the most significant heterocyclic compounds
due to their several chemical reactivities and vital range of biological activity. Although a …
due to their several chemical reactivities and vital range of biological activity. Although a …
Access to phosphine-containing quinazolinones enabled by photo-induced radical phosphorylation/cyclization of unactivated alkenes
B Mu, L Zhang, G Lv, K Chen, T Wang… - The Journal of …, 2022 - ACS Publications
A mild and facile photo-induced cascade radical addition/cyclization of unactivated alkenes
has been reported, through which a variety of biologically valuable phosphine-containing …
has been reported, through which a variety of biologically valuable phosphine-containing …
Rh (iii)-Catalyzed C (sp 2)–H functionalization/cyclization cascade of N-carboxamide indole and iodonium reagents for access to indoloquinazolinone derivatives
ZP Han, MM Xu, RY Zhang, XP Xu, SJ Ji - Green Chemistry, 2021 - pubs.rsc.org
A rhodium-catalyzed synthesis of indoloquinazolinone from a readily available hypervalent
iodonium reagent and N-carboxamide indole was developed. The protocol features broad …
iodonium reagent and N-carboxamide indole was developed. The protocol features broad …
Fungicidal activity of novel quinazolin‐6‐ylcarboxylates and mode of action on Botrytis cinerea
J Xu, D Yan, Y Chen, D Cai, F Huang… - Pest Management …, 2023 - Wiley Online Library
BACKGROUND Fungal diseases remain important causes of crop failure and economic
losses. As the resistance toward current selective fungicides becomes increasingly …
losses. As the resistance toward current selective fungicides becomes increasingly …
Marine biome-derived secondary metabolites, a class of promising antineoplastic agents: A systematic review on their classification, mechanism of action and future …
Cancer is one of the most deadly diseases on the planet. Over the past decades, numerous
antineoplastic compounds have been discovered from natural resources such as medicinal …
antineoplastic compounds have been discovered from natural resources such as medicinal …
[HTML][HTML] Evodiamine induces apoptosis in SMMC-7721 and HepG2 cells by suppressing NOD1 signal pathway
XX Guo, XP Li, P Zhou, DY Li, XT Lyu, Y Chen… - International Journal of …, 2018 - mdpi.com
Hepatocellular cancer (HCC) is a lethal malignancy with poor prognosis and easy
recurrence. There are few agents with minor toxic side effects that can be used for treatment …
recurrence. There are few agents with minor toxic side effects that can be used for treatment …
Acid-catalyzed radical tandem alkylation/cyclization of unactivated alkenes with ketones: Access to ketoalkyl-substituted quinazolinone derivatives
JL Wu, M Yan, LL Fan, CX Mou, JW Yuan, YM ** sickness are potentially fatal diseases that represent a
real health risk for more than 3, 5 billion people. New antiparasitic compounds are urgent …
real health risk for more than 3, 5 billion people. New antiparasitic compounds are urgent …
[HTML][HTML] Chronic pruritus: From pathophysiology to drug design
MS Martins, IF Almeida, MT Cruz, E Sousa - Biochemical Pharmacology, 2023 - Elsevier
Pruritus, the most common symptom in dermatology, is an innate response capable of
protecting skin against irritants. Nonetheless, when it lasts more than six weeks it is …
protecting skin against irritants. Nonetheless, when it lasts more than six weeks it is …