Hepatocellular Carcinoma (HCC) is one of the most common malignant tumours in the
world. It is a heterogeneous group of a tumour that vary in risk factor and genetic and …

Hepatocellular carcinoma (HCC) is one of the most frequent human malignancies worldwide
with very poor prognosis. It is generally accepted that the progression of HCC is a long-term …

The analysis of tumor-derived circulating cell-free DNA opens up new possibilities for
performing liquid biopsies for the assessment of solid tumors. Although its clinical potential …

High invasiveness is a hallmark of human hepatocellular carcinoma (HCC). Large tumors
predict invasion and metastasis. Epithelial‐mesenchymal transition (EMT) is crucial for …

Polyploidy has been described in the liver for over 100 years. The frequency of polyploid
hepatocytes varies by age and species, but up to 90% of mouse hepatocytes and …

Purpose Synovial sarcoma (SS) occurs in both children and adults, although metastatic
events are much more common in adults. Whereas the importance of the t (X; 18) …

Over half of the mature hepatocytes in mice and humans are aneuploid and yet retain full
ability to undergo mitosis. This observation has raised the question of whether this unusual …

A powerful way to identify driver genes with causal roles in carcinogenesis is to detect
genomic regions that undergo frequent alterations in cancers. Here we identified 1,241 …

Hepatoblastoma (HB) is the most common pediatric liver malignancy. High-risk patients
have poor survival, and current chemotherapies are associated with significant toxicities …

The novel oncogene KIF14 (kinesin family member 14) shows genomic gain and
overexpression in many cancers including OvCa (ovarian cancer). We discovered that …