[HTML][HTML] On a highway to the brain: A review on nose-to-brain drug delivery using nanoparticles
The administration of drugs to the central nervous system (CNS) is primarily controlled by
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …
the blood-brain barrier (BBB), a structure that prevents the passage of foreign compounds …
Microneedle array systems for long-acting drug delivery
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …
highly active for more than two decades. The minimally invasive and self-administered MN …
Nanocrystals as a master key to deliver hydrophobic drugs via multiple administration routes
MB McGuckin, J Wang, R Ghanma, N Qin… - Journal of Controlled …, 2022 - Elsevier
The poor aqueous solubility of many approved drugs and most new chemical entities poses
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …
Microneedle patch loaded with exosomes containing microRNA‐29b prevents cardiac fibrosis after myocardial infarction
J Yuan, H Yang, C Liu, L Shao, H Zhang… - Advanced …, 2023 - Wiley Online Library
Myocardial infarction (MI) is a cardiovascular disease that poses a serious threat to human
health. Uncontrolled and excessive cardiac fibrosis after MI has been recognized as a …
health. Uncontrolled and excessive cardiac fibrosis after MI has been recognized as a …
[HTML][HTML] Long-acting microneedle formulations
The minimally-invasive and painless nature of microneedle (MN) application has enabled
the technology to obviate many issues with injectable drug delivery. MNs not only administer …
the technology to obviate many issues with injectable drug delivery. MNs not only administer …
[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
NIR laser‐triggered microneedle‐based liquid band‐aid for wound Care
Microneedles (MNs) have attracted widespread scientific and industrial interest in the past
decade as an efficient, painless, low‐cost, and relatively safe transdermal drug delivery …
decade as an efficient, painless, low‐cost, and relatively safe transdermal drug delivery …
Novel bilayer microarray patch‐assisted long‐acting micro‐depot cabotegravir intradermal delivery for HIV pre‐exposure prophylaxis
Injectable long‐acting cabotegravir (CAB LA) is effective and safe for pre‐exposure HIV
prophylaxis. It is recently approved for clinical use in those at high risk of contracting HIV …
prophylaxis. It is recently approved for clinical use in those at high risk of contracting HIV …
Hydrogel-forming microarray patches with cyclodextrin drug reservoirs for long-acting delivery of poorly soluble cabotegravir sodium for HIV Pre-Exposure Prophylaxis
Hydrogel-forming microarray patches (HF-MAPs) offer minimally invasive, pain-free and
prolonged drug delivery. These devices are designed to be self-administered and self …
prolonged drug delivery. These devices are designed to be self-administered and self …
Selective delivery of silver nanoparticles for improved treatment of biofilm skin infection using bacteria-responsive microparticles loaded into dissolving microneedles
The treatment of infected chronic wounds has been hampered by development of bacterial
biofilms and the low penetration of antibacterial compounds delivered by conventional …
biofilms and the low penetration of antibacterial compounds delivered by conventional …