The pathophysiology of sepsis and its accompanying systemic inflammatory response
syndrome (SIRS) and the events that lead to multiorgan failure and death are poorly …

Long-chain fatty acids are molecules that act as metabolic intermediates and constituents of
membranes; however, their novel role as signaling molecules in immune function has also …

The differentiation and effector functions of both the innate and adaptive immune system are
inextricably linked to cellular metabolism. The features of metabolism which affect both arms …

Free fatty acids (FFAs) play numerous vital roles in the organism, such as contribution to
energy generation and reserve, serving as an essential component of the cell membrane, or …

Research toward the mechanisms underlying obesity-linked complications has intensified
during the last years. As a consequence, it has become clear that metabolism and immunity …

Neutrophils are well-known to act in the destruction of invading microorganisms. They have
also been implicated in the activation of other immune cells including B-and T-lymphocytes …

Metabolic reprogramming of cancer cells creates a unique tumor microenvironment (TME)
characterized by the limited availability of nutrients, which subsequently affects the …

The importance of metabolic pathways for life and the nature of participating reactions have
challenged physiologists and biochemists for over a hundred years. Eric Arthur Newsholme …

Diabetic cardiomyopathy is a term used to describe cardiac muscle damage-induced heart
failure. Multiple structural and biochemical reasons have been suggested to induce this …

Obesity is a major driving factor in the incidence, progression, and poor treatment response
in gastrointestinal cancers. Herein, we conducted a comprehensive analysis of the impact of …