Intracranial hypertension (IH) is a clinical condition commonly encountered in the intensive
care unit, which requires immediate treatment. The maintenance of normal intracranial …

An elevated temperature has many aetiologies, both infective and non-infective, and while
the fever of sepsis probably confers benefit, there is increasing evidence that the central …

Fever in the neurocritical care setting is common and has a negative impact on outcome of
all disease types. Meta-analyses have demonstrated that fever at onset and in the acute …

Background and Purpose—Many studies associate fever with poor outcome in patients with
neurological injury, but this relationship is blurred by divergence in populations and …

Severe excessive autonomic overactivity occurs in a subgroup of people surviving acquired
brain injury, the majority of whom show paroxysmal sympathetic and motor overactivity …

The regulation of brain temperature is largely dependent on the metabolic activity of brain
tissue and remains complex. In intensive care clinical practice, the continuous monitoring of …

Aneurysmal subarachnoid hemorrhage (aSAH) is one of the most severe neurological
disorders, with a high mortality rate and severe disabling functional sequelae. Systemic …

Background Fever suppression may be beneficial for patients with traumatic brain injury
(TBI) and stroke, but for patients with meningitis or encephalitis [central nervous system …

Hyperthermia, frequently seen in patients following traumatic brain injury (TBI), may be due
to posttraumatic cerebral inflammation, direct hypothalamic damage, or secondary infection …

Objective Brain injury remains the leading cause of death in cases of trauma in North
America and Europe. This article critically appraised and summarised all published and …