The protein corona from nanomedicine to environmental science

M Mahmoudi, MP Landry, A Moore… - Nature Reviews Materials, 2023 - nature.com
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Converting nanotoxicity data to information using artificial intelligence and simulation

X Yan, T Yue, DA Winkler, Y Yin, H Zhu… - Chemical …, 2023 - ACS Publications
Decades of nanotoxicology research have generated extensive and diverse data sets.
However, data is not equal to information. The question is how to extract critical information …

Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson's disease

W Jiang, Q Li, R Zhang, J Li, Q Lin, J Li, X Zhou… - Nature …, 2023 - nature.com
Nanomedicine-based anti-neuroinflammation strategy has become a promising dawn of
Parkinson's disease (PD) treatment. However, there are significant gaps in our …

Protein corona-mediated inhibition of nanozyme activity: impact of protein shape

Y Cong, R Qiao, X Wang, Y Ji, J Yang… - Journal of the …, 2024 - ACS Publications
During biomedical applications, nanozymes, exhibiting enzyme-like characteristics,
inevitably come into contact with biological fluids in living systems, leading to the formation …

Physiological barriers and strategies of lipid‐based nanoparticles for nucleic acid drug delivery

M Hu, X Li, Z You, R Cai, C Chen - Advanced Materials, 2024 - Wiley Online Library
Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …

Self-assembled copper tannic acid nanoparticles: a powerful nano-bactericide by valence shift of copper

T Liu, M Ma, A Ali, Q Liu, R Bai, K Zhang, Y Guan… - Nano Today, 2024 - Elsevier
Pathogenic bacterial infection remains a public health problem worldwide. Traditional
antibacterial strategies pose a marked increase in the emergence of drug-resistant strains in …

'Passive'nanoparticles for organ-selective systemic delivery: design, mechanism and perspective

L Fu, Y Zhang, RA Farokhzad, BB Mendes… - Chemical Society …, 2023 - pubs.rsc.org
Nanotechnology has shown tremendous success in the drug delivery field for more effective
and safer therapy, and has recently enabled the clinical approval of RNA medicine, a new …

Engineered living materials for advanced diseases therapy

X Dong, W Wu, P Pan, XZ Zhang - Advanced Materials, 2023 - Wiley Online Library
Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …

Expanding the horizons of machine learning in nanomaterials to chiral nanostructures

V Kuznetsova, Á Coogan, D Botov… - Advanced …, 2024 - Wiley Online Library
Abstract Machine learning holds significant research potential in the field of nanotechnology,
enabling nanomaterial structure and property predictions, facilitating materials design and …

Mechanistic understanding of protein corona formation around nanoparticles: old puzzles and new insights

K Nienhaus, GU Nienhaus - Small, 2023 - Wiley Online Library
Although a wide variety of nanoparticles (NPs) have been engineered for use as disease
markers or drug delivery agents, the number of nanomedicines in clinical use has hitherto …