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Understanding the mechanism of action and clinical effects of neuroactive steroids and GABAergic compounds in major depressive disorder
AJ Cutler, GW Mattingly, V Maletic - Translational Psychiatry, 2023 - nature.com
The pathophysiology of major depressive disorder (MDD) is thought to result from impaired
connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key …
connectivity between key brain networks. Gamma-aminobutyric acid (GABA) is the key …
Right brain, left brain in depressive disorders: clinical and theoretical implications of behavioral, electrophysiological and neuroimaging findings
GE Bruder, JW Stewart, PJ McGrath - Neuroscience & Biobehavioral …, 2017 - Elsevier
The right and left side of the brain are asymmetric in anatomy and function. We review
electrophysiological (EEG and event-related potential), behavioral (dichotic and visual …
electrophysiological (EEG and event-related potential), behavioral (dichotic and visual …
[HTML][HTML] Zuranolone in major depressive disorder: results from MOUNTAIN—a phase 3, multicenter, double-blind, randomized, placebo-controlled trial
AH Clayton, R Lasser, I Nandy, AJ Sankoh… - The Journal of …, 2023 - psychiatrist.com
Objective: To evaluate the efficacy and safety of zuranolone, an investigational neuroactive
steroid and GABA A receptor positive allosteric modulator, in major depressive disorder …
steroid and GABA A receptor positive allosteric modulator, in major depressive disorder …
EEG resting-state large-scale brain network dynamics are related to depressive symptoms
Background: The few previous studies on resting-state electroencephalography (EEG)
microstates in depressive patients suggest altered temporal characteristics of microstates …
microstates in depressive patients suggest altered temporal characteristics of microstates …
Large-scale lesion symptom map** of depression identifies brain regions for risk and resilience
Understanding neural circuits that support mood is a central goal of affective neuroscience,
and improved understanding of the anatomy could inform more targeted interventions in …
and improved understanding of the anatomy could inform more targeted interventions in …
Altered ability to access a clinically relevant control network in patients remitted from major depressive disorder
Neurobiological models to explain vulnerability of major depressive disorder (MDD) are
scarce and previous functional magnetic resonance imaging studies mostly examined …
scarce and previous functional magnetic resonance imaging studies mostly examined …
Transdiagnostic prediction of affective, cognitive, and social function through brain reward anticipation in schizophrenia, bipolar disorder, major depression, and …
K Schwarz, C Moessnang, JI Schweiger… - Schizophrenia …, 2020 - academic.oup.com
The relationship between transdiagnostic, dimensional, and categorical approaches to
psychiatric nosology is under intense debate. To inform this discussion, we studied neural …
psychiatric nosology is under intense debate. To inform this discussion, we studied neural …
Personalized repetitive transcranial magnetic stimulation for depression
Personalized treatments are gaining momentum across all fields of medicine. Precision
medicine can be applied to neuromodulatory techniques, in which focused brain stimulation …
medicine can be applied to neuromodulatory techniques, in which focused brain stimulation …
Experimental suppression of transcranial magnetic stimulation‐electroencephalography sensory potentials
The sensory experience of transcranial magnetic stimulation (TMS) evokes cortical
responses measured in electroencephalography (EEG) that confound interpretation of TMS …
responses measured in electroencephalography (EEG) that confound interpretation of TMS …
Attenuated intrinsic connectivity within cognitive control network among individuals with remitted depression: temporal stability and association with negative cognitive …
Many individuals with major depressive disorder (MDD) experience cognitive dysfunction
including impaired cognitive control and negative cognitive styles. Functional connectivity …
including impaired cognitive control and negative cognitive styles. Functional connectivity …