Brain proton magnetic resonance spectroscopy: introduction and overview

D Bertholdo, A Watcharakorn… - Neuroimaging …, 2013 - neuroimaging.theclinics.com
Magnetic resonance (MR) spectroscopy is an analytical method used in chemistry that
enables the identification and quantification of metabolites in samples. It differs from …

Magnetic resonance spectroscopy

SK Gujar, S Maheshwari… - Journal of neuro …, 2005 - journals.lww.com
Magnetic resonance spectroscopy (MRS) complements magnetic resonance imaging (MRI)
as a non-invasive means for the characterization of tissue. While MRI uses the signal from …

Reduced prefrontal glutamate/glutamine and γ-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy

G Hasler, JW van der Veen, T Tumonis… - Archives of general …, 2007 - jamanetwork.com
Context Increasing evidence indicates that major depressive disorder (MDD) is associated
with altered function of the major excitatory and inhibitory neurotransmitters glutamate and γ …

In vivo 1H NMR spectroscopy of the human brain at 7 T

I Tkáč, P Andersen, G Adriany, H Merkle… - … in Medicine: An …, 2001 - Wiley Online Library
In vivo 1H NMR spectra from the human brain were measured at 7 T. Ultrashort echo‐time
STEAM was used to minimize J‐modulation and signal attenuation caused by the shorter T2 …

Proton T 1 and T 2 relaxation times of human brain metabolites at 3 Tesla

V Mlynárik, S Gruber, E Moser - NMR in Biomedicine: An …, 2001 - Wiley Online Library
Longitudinal and transverse relaxation times were measured for proton MRS signals from
human brain metabolites at 3 T using a short‐echo STEAM protocol and a surface coil as a …

1H metabolite relaxation times at 3.0 tesla: Measurements of T1 and T2 values in normal brain and determination of regional differences in transverse relaxation

F Träber, W Block, R Lamerichs… - Journal of Magnetic …, 2004 - Wiley Online Library
Purpose To measure 1H relaxation times of cerebral metabolites at 3 T and to investigate
regional variations within the brain. Materials and Methods Investigations were performed …

Age-related glutamate and glutamine concentration changes in normal human brain: 1H MR spectroscopy study at 4 T

LG Kaiser, N Schuff, N Cashdollar, MW Weiner - Neurobiology of aging, 2005 - Elsevier
Proton magnetic resonance spectroscopy was performed at 4T to determine effects of age,
region and gender on glutamate and glutamine in the normal human brain. Furthermore …

Short‐echo, single‐shot, full‐intensity proton magnetic resonance spectroscopy for neurochemical profiling at 4 T: validation in the cerebellum and brainstem

G Öz, I Tkáč - Magnetic resonance in medicine, 2011 - Wiley Online Library
A short echo time (TE= 24 ms) semiadiabatic localization by adiabatic selective refocusing
(LASER) sequence was designed and optimized for full‐intensity proton magnetic …

Abnormal glutamatergic neurotransmission and neuronal-glial interactions in acute mania

D Öngür, JE Jensen, AP Prescot, C Stork, M Lundy… - Biological …, 2008 - Elsevier
BACKGROUND: At excitatory synapses, glutamate released from neurons is taken up by
glial cells and converted to glutamine, which is cycled back to neurons. Alterations in this …

In vivo 31P magnetic resonance spectroscopy of human brain at 7 T: An initial experience

H Lei, XH Zhu, XL Zhang, K Ugurbil… - Magnetic Resonance in …, 2003 - Wiley Online Library
In vivo 31P spectra were acquired from the human primary visual cortex at 7 T. The
relaxation times of the cerebral metabolites, intracellular pH, rate constant (kf) of the creatine …