Biosynthesis of the Azoxy Compound Azodyrecin from Streptomyces mirabilis P8-A2
Azoxy compounds are a distinctive group of bioactive secondary metabolites characterized
by a unique RN═ N+ (O–) R moiety. The azoxy moiety is present in various classes of …
by a unique RN═ N+ (O–) R moiety. The azoxy moiety is present in various classes of …
[HTML][HTML] A treasure trove of 1034 actinomycete genomes
Abstract Filamentous Actinobacteria, recently renamed Actinomycetia, are the most prolific
source of microbial bioactive natural products. Studies on biosynthetic gene clusters benefit …
source of microbial bioactive natural products. Studies on biosynthetic gene clusters benefit …
Alligamycin A, an antifungal β-lactone spiroketal macrolide from Streptomyces iranensis
Fungal infections pose a great threat to public health and there are only four main types of
antifungal drugs, which are often limited with toxicity, drug-drug interactions and antibiotic …
antifungal drugs, which are often limited with toxicity, drug-drug interactions and antibiotic …
Genomic Characterization of IMP-Producing Pseudomonas aeruginosa in Bulgaria Reveals the Emergence of IMP-100, a Novel Plasmid-Mediated Variant …
I Stoikov, IN Ivanov, D Donchev, D Teneva, E Dobreva… - Microorganisms, 2023 - mdpi.com
Multidrug-resistant (MDR) Pseudomonas aeruginosa infections represent a major public
health concern and require comprehensive understanding of their genetic makeup. This …
health concern and require comprehensive understanding of their genetic makeup. This …
[HTML][HTML] Genomic Characterization of 16S rRNA Methyltransferase-Producing Enterobacterales Reveals the Emergence of Klebsiella pneumoniae ST6260 Harboring …
S Sabtcheva, I Stoikov, S Georgieva, D Donchev… - Antibiotics, 2024 - mdpi.com
Background: Acquired 16S rRNA methyltransferases (16S-RMTases) confer high-level
resistance to aminoglycosides and are often associated with β-lactam and quinolone …
resistance to aminoglycosides and are often associated with β-lactam and quinolone …
CASCADE-Cas3 Enables Highly Efficient Genome Engineering in Streptomyces Species
Type I CRISPR systems are widespread in bacteria and archaea. The main differences
compared to more widely applied type II systems are multi-effector CASCADE needed for …
compared to more widely applied type II systems are multi-effector CASCADE needed for …
Genomic Characterization of Carbapenemase-Producing Enterobacter hormaechei, Serratia marcescens, Citrobacter freundii, Providencia stuartii, and Morganella …
S Sabtcheva, I Stoikov, IN Ivanov, D Donchev… - Antibiotics, 2024 - mdpi.com
Carbapenemase-producing Enterobacter spp. Serratia marcescens, Citrobacter freundii,
Providencia spp., and Morganella morganii (CP-ESCPM) are increasingly identified as …
Providencia spp., and Morganella morganii (CP-ESCPM) are increasingly identified as …
Properties of Multidrug-Resistant Mutants Derived from Heterologous Expression Chassis Strain Streptomyces albidoflavus J1074
B Dolya, O Hryhorieva, K Sorochynska, M Lopatniuk… - Microorganisms, 2023 - mdpi.com
Streptomyces albidoflavus J1074 is a popular platform to discover novel natural products via
the expression of heterologous biosynthetic gene clusters (BGCs). There is keen interest in …
the expression of heterologous biosynthetic gene clusters (BGCs). There is keen interest in …
Complete genome sequences of the two strains Methylorubrum Extorquens Nbc_00036 and Nbc_00404
D Faurdal, TS Jørgensen… - Microbiology …, 2023 - Am Soc Microbiol
Here, we report the complete genome sequences of Methylorubrum extorquens
NBC_00036 and Methylorubrum extorquens NBC_00404. The genomes were sequenced …
NBC_00036 and Methylorubrum extorquens NBC_00404. The genomes were sequenced …
Complete, circular genome sequence of a Bosea sp. isolate from soil
M Alvarez-Arevalo, EB Sterndorff… - Microbiology …, 2023 - Am Soc Microbiol
Here, we report the complete, circular genome sequence of a potential novel species from
the underexplored Alphaproteobacterial genus Bosea. Bosea sp. NBC_00550 was isolated …
the underexplored Alphaproteobacterial genus Bosea. Bosea sp. NBC_00550 was isolated …