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Calcium-release channels: structure and function of IP3 receptors and ryanodine receptors
KA Woll, F Van Petegem - Physiological Reviews, 2022 - journals.physiology.org
Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …
[HTML][HTML] Interrelation between ROS and Ca2+ in aging and age-related diseases
Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …
molecules coordinating physiological and pathophysiological processes. While channels …
The ion channels of endomembranes
M Hu, X Feng, Q Liu, S Liu, F Huang… - Physiological …, 2024 - journals.physiology.org
The endomembrane system consists of organellar membranes in the biosynthetic pathway
[endoplasmic reticulum (ER), Golgi apparatus, and secretory vesicles] as well as those in the …
[endoplasmic reticulum (ER), Golgi apparatus, and secretory vesicles] as well as those in the …
KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals
NB Thillaiappan, HA Smith, P Atakpa-Adaji… - Nature …, 2021 - nature.com
Regulation of IP3 receptors (IP3Rs) by IP3 and Ca2+ allows regenerative Ca2+ signals, the
smallest being Ca2+ puffs, which arise from coordinated openings of a few clustered IP3Rs …
smallest being Ca2+ puffs, which arise from coordinated openings of a few clustered IP3Rs …
Structural titration reveals Ca2+-dependent conformational landscape of the IP3 receptor
Abstract Inositol 1, 4, 5-trisphosphate receptors (IP3Rs) are endoplasmic reticulum Ca2+
channels whose biphasic dependence on cytosolic Ca2+ gives rise to Ca2+ oscillations that …
channels whose biphasic dependence on cytosolic Ca2+ gives rise to Ca2+ oscillations that …
In the Right Place at the Right Time: Regulation of Cell Metabolism by IP3R-Mediated Inter-Organelle Ca2+ Fluxes
U Ahumada-Castro, G Bustos, E Silva-Pavez… - Frontiers in cell and …, 2021 - frontiersin.org
In the last few years, metabolism has been shown to be controlled by cross-organelle
communication. The relationship between the endoplasmic reticulum and mitochondria …
communication. The relationship between the endoplasmic reticulum and mitochondria …
Models of stochastic spiking: Established approaches and inspirations from models of neuronal spikes
Complexity and limited knowledge render it impractical to write down the equations
describing a cellular system completely. Cellular biophysics uses hypotheses-based …
describing a cellular system completely. Cellular biophysics uses hypotheses-based …
The interplay between associated proteins, redox state and Ca2+ in the intraluminal ER compartment regulates the IP3 receptor
JB Parys, FO Lemos - Cell Calcium, 2024 - Elsevier
There have been in the last three decades repeated publications indicating that the inositol
1, 4, 5-trisphosphate receptor (IP 3 R) is regulated not only by cytosolic Ca 2+ but also by …
1, 4, 5-trisphosphate receptor (IP 3 R) is regulated not only by cytosolic Ca 2+ but also by …
Annexin-and calcium-regulated priming of legume root cells for endosymbiotic infection
A Guillory, J Fournier, A Kelner, K Hobecker… - Nature …, 2024 - nature.com
Legumes establish endosymbioses with arbuscular mycorrhizal (AM) fungi or rhizobia
bacteria to improve mineral nutrition. Symbionts are hosted in privileged habitats, root cortex …
bacteria to improve mineral nutrition. Symbionts are hosted in privileged habitats, root cortex …
[HTML][HTML] Phosphatidylinositol 4, 5-bisphosphate and calcium at ER-PM junctions—Complex interplay of simple messengers
A Ivanova, P Atakpa-Adaji - Biochimica et Biophysica Acta (BBA)-Molecular …, 2023 - Elsevier
Endoplasmic reticulum-plasma membrane contact sites (ER-PM MCS) are a specialised
domain involved in the control of Ca 2+ dynamics and various Ca 2+-dependent cellular …
domain involved in the control of Ca 2+ dynamics and various Ca 2+-dependent cellular …