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Clinical and biomedical applications of lensless holographic microscopy
Many clinical procedures and biomedical research workflows rely on microscopy, including
diagnosis of cancer, genetic disorders, autoimmune diseases, infections, and quantification …
diagnosis of cancer, genetic disorders, autoimmune diseases, infections, and quantification …
Deep-learning-augmented computational miniature mesoscope
Fluorescence microscopy is essential to study biological structures and dynamics. However,
existing systems suffer from a trade-off between field of view (FOV), resolution, and system …
existing systems suffer from a trade-off between field of view (FOV), resolution, and system …
Mesoscopic calcium imaging in a head-unrestrained male non-human primate using a lensless microscope
Mesoscopic calcium imaging enables studies of cell-type specific neural activity over large
areas. A growing body of literature suggests that neural activity can be different when …
areas. A growing body of literature suggests that neural activity can be different when …
Design and single-shot fabrication of lensless cameras with arbitrary point spread functions
Lensless cameras are a novel class of computational imaging devices, in which the lenses
are replaced with a thin mask to achieve ultra-compact and low-cost hardware. In this paper …
are replaced with a thin mask to achieve ultra-compact and low-cost hardware. In this paper …
Large depth-of-field ultra-compact microscope by progressive optimization and deep learning
The optical microscope is customarily an instrument of substantial size and expense but
limited performance. Here we report an integrated microscope that achieves optical …
limited performance. Here we report an integrated microscope that achieves optical …
Ptychographic lens-less birefringence microscopy using a mask-modulated polarization image sensor
Birefringence, an inherent characteristic of optically anisotropic materials, is widely utilized
in various imaging applications ranging from material characterizations to clinical diagnosis …
in various imaging applications ranging from material characterizations to clinical diagnosis …
Direct laser writing-enabled 3D printing strategies for microfluidic applications
Over the past decade, additive manufacturing—or “three-dimensional (3D) printing”—has
attracted increasing attention in the Lab on a Chip community as a pathway to achieve …
attracted increasing attention in the Lab on a Chip community as a pathway to achieve …
DeepDOF-SE: affordable deep-learning microscopy platform for slide-free histology
Histopathology plays a critical role in the diagnosis and surgical management of cancer.
However, access to histopathology services, especially frozen section pathology during …
However, access to histopathology services, especially frozen section pathology during …
A subdural CMOS optical device for bidirectional neural interfacing
Optical neurotechnologies use light to interface with neurons and can monitor and
manipulate neural activity with high spatial-temporal precision over large cortical areas …
manipulate neural activity with high spatial-temporal precision over large cortical areas …
Real-time, deep-learning aided lensless microscope
Traditional miniaturized fluorescence microscopes are critical tools for modern biology.
Invariably, they struggle to simultaneously image with a high spatial resolution and a large …
Invariably, they struggle to simultaneously image with a high spatial resolution and a large …