Type 1 diabetes is a chronic autoimmune disease characterised by insulin deficiency and
resultant hyperglycaemia. Knowledge of type 1 diabetes has rapidly increased over the past …

Glycemic control, a worthwhile goal for people with diabetes, is limited by the barrier of iatro-
genic hypoglycemia (1). Iatrogenic hypoglycemia 1) causes recurrent morbidity in most …

Objective: To review the evidence about the impact of hypoglycemia on patients with
diabetes that has become available since the past reviews of this subject by the American …

Background Patients with type 1 diabetes who have impaired awareness of hypoglycaemia
have a three to six times increased risk of severe hypoglycaemia. We aimed to assess …

• If unexplained hypoglycemia is frequent, evaluation for unrecognized celiac and Addison's
disease should be considered (E).• Currently available technologies like CGM, automated …

Problematic hypoglycemia, defined as two or more episodes per year of severe
hypoglycemia or as one episode associated with impaired awareness of hypoglycemia …

The selection of a glycemic goal in a person with diabetes is a compromise between the
documented upside of glycemic control—the partial prevention or delay of microvascular …

OBJECTIVE To assess the safety and efficacy of dual sodium–glucose cotransporter (SGLT)
1 and SGLT2 inhibition with sotagliflozin as adjunct therapy to insulin in type 1 diabetes …

Hypoglycemia caused by treatment with a sulfonylurea, a glinide, or insulin coupled with
compromised defenses against the resulting falling plasma glucose concentrations is a …

The brain relies almost exclusively on glucose for fuel. Therefore, adequate uptake of
glucose from the plasma is key for normal brain function and survival. Despite wide …