Advances in cell-conductive polymer biointerfaces and role of the plasma membrane

A Mariano, C Lubrano, U Bruno, C Ausilio… - Chemical …, 2021 - ACS Publications
The plasma membrane (PM) is often described as a wall, a physical barrier separating the
cell cytoplasm from the extracellular matrix (ECM). Yet, this wall is a highly dynamic structure …

Quartz crystal microbalance with dissipation monitoring for studying soft matter at interfaces

D Johannsmann, I Reviakine - Nature Reviews Methods Primers, 2024 - nature.com
Quartz crystal microbalance with dissipation monitoring (QCM-D) probes interfaces by
subjecting them to a periodic shear stress exerted by an acoustic resonator. The changes in …

Supported lipid bilayer formation: beyond vesicle fusion

JA Jackman, NJ Cho - Langmuir, 2020 - ACS Publications
Supported lipid bilayers (SLBs) are cell-membrane-mimicking platforms that can be formed
on solid surfaces and integrated with a wide range of surface-sensitive measurement …

Phase-separating peptide coacervates with programmable material properties for universal intracellular delivery of macromolecules

Y Sun, X Wu, J Li, M Radiom, R Mezzenga… - Nature …, 2024 - nature.com
Phase-separating peptides (PSPs) self-assembling into coacervate microdroplets (CMs) are
a promising class of intracellular delivery vehicles that can release macromolecular …

Membrane curvature regulates the spatial distribution of bulky glycoproteins

CH Lu, K Pedram, CT Tsai, T Jones IV, X Li… - Nature …, 2022 - nature.com
The glycocalyx is a shell of heavily glycosylated proteins and lipids distributed on the cell
surface of nearly all cell types. Recently, it has been found that bulky transmembrane …

Supported Lipid Bilayers Coupled to Organic Neuromorphic Devices Modulate Short‐Term Plasticity in Biomimetic Synapses

C Lubrano, U Bruno, C Ausilio, F Santoro - Advanced Materials, 2022 - Wiley Online Library
Synaptic plasticity is a fundamental process for neuronal communication and is involved in
neurodegeneration. This process has been recently exploited to inspire the design of next …

Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform

A Stollmann, J Garcia-Guirado, JS Hong… - Nature …, 2024 - nature.com
Label-free detection of multiple analytes in a high-throughput fashion has been one of the
long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing …

Observation of liquid–liquid-phase separation and vesicle spreading during supported bilayer formation via liquid-phase transmission electron microscopy

A Rizvi, JT Mulvey, JP Patterson - Nano Letters, 2021 - ACS Publications
Liquid-phase transmission electron microscopy (LP-TEM) enables the real-time visualization
of nanoscale dynamics in solution. This technique has been used to study the formation and …

An impedance-based approach for sensing cyclodextrin-mediated modulation of membrane cholesterol

SF Bint E Naser, HY Liu, H Su, A Kouloumpis… - Langmuir, 2023 - ACS Publications
Cyclodextrin molecules are increasingly being used in biological research and as
therapeutic agents to alter membrane cholesterol content, yet there is much to learn about …

Hybrid Supported Lipid Bilayers for Bioinspired Bioelectronics with Enhanced Stability

EA Schafer, E Davis, Z Manzer, S Daniel… - ACS Applied Materials …, 2023 - ACS Publications
A promising new class of biosensors leverages the sensing mechanisms of living cells by
incorporating native transmembrane proteins into biomimetic membranes. Conducting …