Insights into epileptogenesis from post-traumatic epilepsy

M Pease, K Gupta, SL Moshé, DJ Correa… - Nature Reviews …, 2024 - nature.com
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after
traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in …

[HTML][HTML] Using artificial intelligence to optimize anti-seizure treatment and EEG-guided decisions in severe brain injury

Z Akras, J **g, MB Westover, SF Zafar - Neurotherapeutics, 2025 - Elsevier
Electroencephalography (EEG) is invaluable in the management of acute neurological
emergencies. Characteristic EEG changes have been identified in diverse neurologic …

EEG biomarkers for the prediction of post-traumatic epilepsy-a systematic review of an emerging field

J Pyrzowski, M Kałas… - … : European Journal of …, 2024 - Elsevier
Traumatic brain injury (TBI) is often followed by post-traumatic epilepsy (PTE), a condition
often difficult to treat and leading to a substantial decline in quality of life as well as …

Exploring multimodal biomarker candidates of post‐traumatic epilepsy following moderate to severe traumatic brain injury: A systematic review and meta‐analysis

AA Bruckhaus, T Asifriyaz, K Kriukova, TJ O'Brien… - …, 2025 - Wiley Online Library
This review systematically analyzes potential biomarker candidates for post‐traumatic
epilepsy (PTE) in humans who have experienced moderate to severe traumatic brain injury …

[HTML][HTML] Utility of Electroencephalograms for Enhancing Clinical Care and Rehabilitation of Children with Acquired Brain Injury

K Politi, PL Weiss, K Givony… - International Journal of …, 2024 - mdpi.com
The objective of this literature review was to present evidence from recent studies and
applications focused on employing electroencephalogram (EEG) monitoring and …

Early hippocampal high-amplitude rhythmic spikes predict post-traumatic epilepsy in mice

T Shannon, N Levine, R Dirickson, Y Shen… - Frontiers in …, 2024 - frontiersin.org
Oscillations, a highly conserved brain function across mammalian species, play a pivotal
role in both brain physiology and pathology. Traumatic brain injury (TBI) frequently results in …

Early Post-Traumatic Seizures After Severe Traumatic Brain Injury

M Pease, J Elmer, AN Mallela… - Neurotrauma …, 2024 - liebertpub.com
Seizures are common after severe traumatic brain injury (TBI), with rates in the acute period
approaching 5% with seizure prophylaxis in historical clinical trials. Post-traumatic seizures …

Prognostic Implications of Early Prediction in Posttraumatic Epilepsy

Y Chen, SP Cappucci, JA Kim - Seminars in Neurology, 2024 - thieme-connect.com
Posttraumatic epilepsy (PTE) is a complication of traumatic brain injury that can increase
morbidity, but predicting which patients may develop PTE remains a challenge. Much work …

The predicative value of early quantitative electroencephalograph in epilepsy after severe traumatic brain injury in children

W Bai - Frontiers in Pediatrics, 2024 - frontiersin.org
Objective To explore whether early quantitative electroencephalograph (EEG) can predict
the development of epilepsy in pediatric patients with severe traumatic brain injury (TBI) …

Computational Prognostic Modeling in Traumatic Brain Injury

M Pease, D Arefan, FM Hammond… - Computational …, 2024 - Springer
Traumatic brain injury is the leading cause of death and disability worldwide. Despite this
large impact, no predictive models are in widespread use due to tedious data collection …