Microneedle-based biosensing

LK Vora, AH Sabri, PE McKenna, A Himawan… - Nature Reviews …, 2024 - nature.com
Microneedles (MNs) are microscopic needles that are applied to the skin in a minimally
invasive way to facilitate transdermal drug delivery and/or uptake of interstitial fluid from the …

Recent progress, challenges, and prospects of fully integrated mobile and wearable point-of-care testing systems for self-testing

S Shrivastava, TQ Trung, NE Lee - Chemical Society Reviews, 2020 - pubs.rsc.org
The rapid growth of research in the areas of chemical and biochemical sensors, lab-on-a-
chip, mobile technology, and wearable electronics offers an unprecedented opportunity in …

Microneedle aptamer-based sensors for continuous, real-time therapeutic drug monitoring

Y Wu, F Tehrani, H Teymourian, J Mack… - Analytical …, 2022 - ACS Publications
The ability to continuously monitor the concentration of specific molecules in the body is a
long-sought goal of biomedical research. For this purpose, interstitial fluid (ISF) was …

Lab under the skin: microneedle based wearable devices

H Teymourian, F Tehrani, K Mahato… - Advanced healthcare …, 2021 - Wiley Online Library
While the current smartwatches and cellphones can readily track mobility and vital signs, a
new generation of wearable devices is rapidly develo** to enable users to monitor their …

Interstitial fluid-based wearable biosensors for minimally invasive healthcare and biomedical applications

Z Wu, Z Qiao, S Chen, S Fan, Y Liu, J Qi… - Communications …, 2024 - nature.com
Interstitial fluid (ISF), a biological fluid rich in diverse biomarkers and analytes and similar to
blood composition, has garnered significant attention as a valuable source of clinically …

Artificial intelligence biosensors: Challenges and prospects

X **, C Liu, T Xu, L Su, X Zhang - Biosensors and Bioelectronics, 2020 - Elsevier
Artificial intelligence (AI) and wearable sensors are two essential fields to realize the goal of
tailoring the best precision medicine treatment for individual patients. Integration of these …

Wearable Clinic: From Microneedle‐Based Sensors to Next‐Generation Healthcare Platforms

H Sun, Y Zheng, G Shi, H Haick, M Zhang - Small, 2023 - Wiley Online Library
The rapid development of wearable biosensing calls for next‐generation devices that allow
continuous, real‐time, and painless monitoring of health status along with responsive …

Enzyme‐based glucose sensor: from invasive to wearable device

H Lee, YJ Hong, S Baik, T Hyeon… - Advanced healthcare …, 2018 - Wiley Online Library
Blood glucose concentration is a key indicator of patients' health, particularly for symptoms
associated with diabetes mellitus. Because of the large number of diabetic patients, many …

Microneedle-based transdermal detection and sensing devices

J Wang, Z Lu, R Cai, H Zheng, J Yu, Y Zhang, Z Gu - Lab on a Chip, 2023 - pubs.rsc.org
Microneedles have been expected for the construction of next-generation biosensors
towards personalization, digitization, and intellectualization due to their metrics of minimal …

Wearable electrochemical microneedle sensor for continuous monitoring of levodopa: toward Parkinson management

KY Goud, C Moonla, RK Mishra, C Yu, R Narayan… - ACS …, 2019 - ACS Publications
Levodopa is the most effective medication for treating Parkinson's disease (PD). However,
because dose optimization is currently based on patients' report of symptoms, which are …