▪ Abstract Olfaction begins with the transduction of the information carried by odor molecules
into electrical signals in sensory neurons. The activation of different subsets of sensory …

Olfaction is often referred to as a multidimensional sense. It is multidimensional in that∼
1000 different receptor types, each tuned to particular odor aspects, together contribute to …

The mammalian olfactory system can recognize and discriminate a large number of different
odorant molecules. The detection of chemically distinct odorants presumably results from the …

Olfaction is a versatile and sensitive mechanism for detecting volatile odorants. We show
that the nematode C. elegans detects many volatile chemicals, which can be attractants …

Biochemical and electrophysiological studies suggest that odorants induce responses in
olfactory sensory neurons via an adenylate cyclase cascade mediated by a G protein. An …

Olfactory transduction is thought to be initiated by the binding of odorants to specific receptor
proteins in the cilia of olfactory receptor cells (reviewed in refs 1–3). The mechanism by …

The largest collection of basic, clinical, and applied knowledge on the chemical senses ever
compiled in one volume, the third edition of Handbook of Olfaction and Gustation …

Olfactory signaling is initiated by interactions between odorants and olfactory receptors. We
show that the C. elegans odr-10 gene is likely to encode a receptor for the odorant diacetyl …

We have used gene targeting to examine the role of the Gα subunit, G olf, in olfactory signal
transduction. Mice homozygous for a null mutation in G olf show a striking reduction in the …

The mammalian olfactory system may transduce odorant information via a G protein-
mediated adenosine 3′, 5′-monophosphate (cAMP) cascade. A newly discovered …