Museum of spatial transcriptomics
The function of many biological systems, such as embryos, liver lobules, intestinal villi, and
tumors, depends on the spatial organization of their cells. In the past decade, high …
tumors, depends on the spatial organization of their cells. In the past decade, high …
[HTML][HTML] MicroRNAs: target recognition and regulatory functions
DP Bartel - cell, 2009 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 23 nt RNAs that play important gene-regulatory
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
Circulating microRNAs as stable blood-based markers for cancer detection
PS Mitchell, RK Parkin, EM Kroh… - Proceedings of the …, 2008 - National Acad Sciences
Improved approaches for the detection of common epithelial malignancies are urgently
needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs …
needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs …
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Epithelial to mesenchymal transition (EMT) facilitates tissue remodelling during embryonic
development and is viewed as an essential early step in tumour metastasis. We found that …
development and is viewed as an essential early step in tumour metastasis. We found that …
Many roads to maturity: microRNA biogenesis pathways and their regulation
J Winter, S Jung, S Keller, RI Gregory… - Nature cell biology, 2009 - nature.com
MicroRNAs are important regulators of gene expression that control both physiological and
pathological processes such as development and cancer. Although their mode of action has …
pathological processes such as development and cancer. Although their mode of action has …
MicroRNA-mediated regulation of glucose and lipid metabolism
P Agbu, RW Carthew - Nature reviews Molecular cell biology, 2021 - nature.com
In animals, systemic control of metabolism is conducted by metabolic tissues and relies on
the regulated circulation of a plethora of molecules, such as hormones and lipoprotein …
the regulated circulation of a plethora of molecules, such as hormones and lipoprotein …
MicroRNA profiling: approaches and considerations
CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …
thousands of genes in a broad range of organisms in both normal physiological contexts …
[HTML][HTML] A mammalian microRNA expression atlas based on small RNA library sequencing
MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or
translation of fully or partially sequence-complementary target mRNAs. In order to identify …
translation of fully or partially sequence-complementary target mRNAs. In order to identify …
microRNA functions
N Bushati, SM Cohen - Annu. Rev. Cell Dev. Biol., 2007 - annualreviews.org
microRNAs (miRNAs) are small noncoding RNAs that play important roles in
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …
posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by …
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation
JF Chen, EM Mandel, JM Thomson, Q Wu, TE Callis… - Nature …, 2006 - nature.com
Understanding the molecular mechanisms that regulate cellular proliferation and
differentiation is a central theme of developmental biology. MicroRNAs (miRNAs) are a class …
differentiation is a central theme of developmental biology. MicroRNAs (miRNAs) are a class …