Anisotropic conductive reduced graphene oxide/silk matrices promote post-infarction myocardial function by restoring electrical integrity

G Zhao, Y Feng, L Xue, M Cui, Q Zhang, F Xu, N Peng… - Acta Biomaterialia, 2022 - Elsevier
Myocardial infarction (MI) remains the leading cause of death globally, often leading to
impaired cardiac function and pathological myocardial microenvironment. Electrical …

Approaches for determining cardiac bidomain conductivity values: progress and challenges

BM Johnston, PR Johnston - Medical & biological engineering & …, 2020 - Springer
Modelling the electrical activity of the heart is an important tool for understanding electrical
function in various diseases and conduction disorders. Clearly, for model results to be …

[HTML][HTML] Progress of Conductivity and Conduction Velocity Measured in Human and Animal Hearts

Z Fu, R Dong, H Zheng, Z Wang, B Cao… - Reviews in …, 2024 - pmc.ncbi.nlm.nih.gov
Cardiac conduction velocity (CV) is a critical electrophysiological characteristic of the
myocardium, representing the speed at which electrical pulses propagate through cardiac …

A smoothed boundary bidomain model for cardiac simulations in anatomically detailed geometries

N Biasi, P Seghetti, M Mercati, A Tognetti - PloS one, 2023 - journals.plos.org
This manuscript presents a novel finite difference method to solve cardiac bidomain
equations in anatomical models of the heart. The proposed method employs a smoothed …

Confocal microscopy-based estimation of parameters for computational modeling of electrical conduction in the normal and infarcted heart

J Greiner, AC Sankarankutty, G Seemann… - Frontiers in …, 2018 - frontiersin.org
Computational modeling is an important tool to advance our knowledge on cardiac diseases
and their underlying mechanisms. Computational models of conduction in cardiac tissues …

Quantifying the effect of uncertainty in input parameters in a simplified bidomain model of partial thickness ischaemia

BM Johnston, S Coveney, ETY Chang… - Medical & biological …, 2018 - Springer
Reduced blood flow in the coronary arteries can lead to damaged heart tissue (myocardial
ischaemia). Although one method for detecting myocardial ischaemia involves changes in …

[HTML][HTML] An explicit local space-time adaptive framework for monodomain models in cardiac electrophysiology

D Ogiermann, D Balzani, LE Perotti - Computer Methods in Applied …, 2024 - Elsevier
We present a new explicit local space–time adaptive framework to decrease the time
required for monodomain simulations for cardiac electrophysiology. Based on the localized …

Impedance and conductivity of bovine myocardium during freezing and thawing at slow rates-implications for cardiac cryo–ablation

G Fischer, M Handler, PR Johnston… - Medical engineering & …, 2019 - Elsevier
Increasing impedance during freezing might be a valuable marker for guiding cardiac cryo-
ablation. We provide model based insights on how decreasing temperature below the …

[HTML][HTML] Generation of a cohort of whole-torso cardiac models for assessing the utility of a novel computed shock vector efficiency metric for ICD optimisation

AM Plancke, A Connolly, PM Gemmell, A Neic… - Computers in biology …, 2019 - Elsevier
Implanted cardiac defibrillators (ICDs) seek to automatically detect and terminate potentially
lethal ventricular arrhythmias by applying strong internal electric shocks across the heart …

Confocal microscopy-based estimation of intracellular conductivities in myocardium for modeling of the normal and infarcted heart

J Greiner, AC Sankarankutty, T Seidel… - Computers in biology and …, 2022 - Elsevier
Ventricular arrhythmias are the leading cause of mortality in patients with ischemic heart
diseases, such as myocardial infarction (MI). Computational simulation of cardiac …