MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by
degrading or repressing the translation of their target messenger RNAs. As miRNAs are …

The observation that unhealthy diets (those that are low in whole grains, fruits and
vegetables, and high in sugar, salt, saturated fat and ultra-processed foods) are a major risk …

Systemic inflammation in end-stage renal disease is an established risk factor for mortality
and a catalyst for other complications, which are related to a premature aging phenotype …

Delayed graft function (DGF) remains a major barrier to improved outcomes after kidney
transplantation. High‐risk transplant recipients can be identified, but no definitive prediction …

An ability to separate natural ageing processes from processes specific to morbidities is
required to understand the heterogeneity of age-related organ dysfunction. Mechanistic …

MicroRNAs are epigenetic regulators of gene expression at the posttranscriptional level.
They are involved in intercellular communication and crosstalk between different organs. As …

Genomics, proteomics and molecular biology lead to tremendous advances in all fields of
medical sciences. Among these the finding of biomarkers as non invasive indicators of …

Abstract Delayed Graft Function (DGF) is one of the most common early complications in
kidney transplantation, associated with poor graft outcomes, prolonged post-operative …

Multiple myeloma (MM) is a disease of aging adults and autologous stem cell transplant
(ASCT) is considered the standard of care. As the population ages a growing number of …

Background A long-standing effort is dedicated towards the identification of biomarkers
allowing the prediction of graft outcome after kidney transplant. Extracellular vesicles (EVs) …