People with diabetes and chronic kidney disease (CKD) are at high risk for kidney failure,
atherosclerotic cardiovascular disease, heart failure, and premature mortality. Recent …

Cardiovascular diseases (CVDs) continue to be a major global health concern, representing
a leading cause of morbidity and mortality. This review provides a comprehensive …

Abstract Purpose of Review This review describes the discovery and development of ACE
inhibitors as antihypertensive agents, compares their efficacy, tolerability, and safety to …

Hypertension represents a major common cardiovascular risk factor. Optimal control of high
blood pressure levels is recommended to reduce the global burden of hypertensive …

Traumatic brain injury (TBI) is a major public health problem, with limited pharmacological
options available beyond symptomatic relief. The renin angiotensin system (RAS) is …

The health burden of ischemic stroke is high and will continue to increase with an aging
population. Recurrent ischemic stroke is increasingly recognized as a major public health …

Aims The metabolic failure of macrophages to adequately process lipid is central to the
aetiology of atherosclerosis. Here, we examine the role of macrophage angiotensin …

Abstract Purpose of Review To provide an overview of the association between angiotensin
II receptor blocker (ARB) use and cognitive outcomes. Recent Findings ARBs have …

Hypertension (HTN) is the leading cause of premature deaths worldwide and the main
preventable risk factor for cardiovascular diseases. Therefore, there is a current need for …

Opinion statement The renin–angiotensin–aldosterone system (RAAS) is a crucial regulator
of the cardiovascular system and a target for widely used therapeutic drugs. Dysregulation of …