The effects of cell therapy on heart regeneration in patients with chronic cardiomyopathy
have been assessed in several clinical trials. These trials can be categorized as those using …

Exosomes are nanosized membrane particles that are secreted by cells that transmit
information from cell to cell. The information within exosomes prominently includes their …

Summary Background Cardiosphere-derived cells (CDCs) reduce scarring after myocardial
infarction, increase viable myocardium, and boost cardiac function in preclinical models. We …

Cardiosphere‐derived cells (CDC s) reduce myocardial infarct size via secreted
extracellular vesicles (CDC‐EVs), including exosomes, which alter macrophage …

Cardiosphere‐derived cells (CDCs) have been shown to regenerate infarcted myocardium
in patients after myocardial infarction (MI). However, whether the cells of the newly formed …

Heart failure (HF) is a complex clinical syndrome resulting from diverse primary and
secondary causes and shared pathways of disease progression, correlating with substantial …

Background—Cardiosphere-derived cells (CDCs) are an attractive cell type for tissue
regeneration, and autologous CDCs are being tested clinically. However, autologous …

A major limitation to cardiac tissue engineering and regenerative medicine strategies is the
lack of proliferation of postnatal cardiomyocytes. The extracellular matrix (ECM) is altered …

Cardiac failure is a critical condition that results in life-threatening consequences. Due to a
limited number of organ donors, tissue engineering has emerged to generate functional …

Introduction Stem cell therapy has emerged as a promising strategy for the treatment of
ischemic cardiomyopathy. Sources of data Multiple candidate cell types have been used in …