Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches

K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …

Vaccine delivery systems toward lymph nodes

Y Ding, Z Li, A Jaklenec, Q Hu - Advanced drug delivery reviews, 2021 - Elsevier
Strategies of improving vaccine targeting ability toward lymph nodes have been attracting
considerable interest in recent years, though there are remaining delivery barriers based on …

Virus-like particles: fundamentals and biomedical applications

JL Mejía-Méndez, R Vazquez-Duhalt… - International journal of …, 2022 - mdpi.com
Nanotechnology is a fast-evolving field focused on fabricating nanoscale objects for
industrial, cosmetic, and therapeutic applications. Virus-like particles (VLPs) are self …

Nanocarriers for the delivery of medical, veterinary, and agricultural active ingredients

PL Chariou, OA Ortega-Rivera, NF Steinmetz - Acs Nano, 2020 - ACS Publications
Nanocarrier-based delivery systems can be used to increase the safety and efficacy of active
ingredients in medical, veterinary, or agricultural applications, particularly when such …

Virus-like particles as preventive and therapeutic cancer vaccines

AL Tornesello, M Tagliamonte, FM Buonaguro… - Vaccines, 2022 - mdpi.com
Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …

Tumor cell membrane enveloped aluminum phosphate nanoparticles for enhanced cancer vaccination

J Gan, G Du, C He, M Jiang, X Mou, J Xue… - Journal of Controlled …, 2020 - Elsevier
An ideal cancer vaccine should contain both strongly immunogenic cancer-specific antigen
and potent adjuvant for stimulating robust cellular immunity which are pivotal for clearance …

Precise assembly of proteins and carbohydrates for next-generation biomaterials

L Li, G Chen - Journal of the American Chemical Society, 2022 - ACS Publications
The complexity and diversity of biomacromolecules make them a unique class of building
blocks for generating precise assemblies. They are particularly available to a new …

Four ounces can move a thousand pounds: the enormous value of nanomaterials in tumor immunotherapy

Z Chen, Z Yue, K Yang, C Shen… - Advanced …, 2023 - Wiley Online Library
The application of nanomaterials in healthcare has emerged as a promising strategy due to
their unique structural diversity, surface properties, and compositional diversity. In particular …

Application of nano-delivery systems in lymph nodes for tumor immunotherapy

Y **a, S Fu, Q Ma, Y Liu, N Zhang - Nano-micro letters, 2023 - Springer
Immunotherapy has become a promising research “hotspot” in cancer treatment.“Soldier”
immune cells are not uniform throughout the body; they accumulate mostly in the immune …