FOXO proteins are transcription factors that are involved in numerous physiological
processes and in various pathological conditions, including cardiovascular disease, cancer …

Acne vulgaris is a cutaneous chronic inflammatory disorder with complex pathogenesis.
Four factors play vital roles in acne pathophysiology: hyperseborrhea and dysseborrhea …

Forkhead box (Fox) proteins are a superfamily of evolutionarily conserved transcriptional
regulators, which control a wide spectrum of biological processes. As a consequence, a loss …

Acne vulgaris is a common dermatological condition that can present across different ages
but predominantly affects adolescents and young adults. Characterized by various lesion …

Acne vulgaris, an epidemic inflammatory skin disease of adolescence, is closely related to
Western diet. Three major food classes that promote acne are: 1) hyperglycemic …

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway regulates
cell proliferation, differentiation, and migration, along with angiogenesis and metabolism …

Acne vulgaris is an epidemic inflammatory disease of the human sebaceous follicle and
represents the most common skin disease affecting about 85% of adolescents in …

This review on acne transcriptomics allows for deeper insights into the pathogenesis of acne
and isotretinoin's mode of action. Puberty-induced insulin-like growth factor 1 (IGF-1), insulin …

The discovery of the benefits of castration for prostate cancer treatment in 1941 led to
androgen deprivation therapy, which remains a mainstay of the treatment of men with …

It is the purpose of this viewpoint article to delineate the regulatory network of growth
hormone (GH), insulin, and insulin‐like growth factor‐1 (IGF‐1) signalling during puberty …