Unusual biophysics of intrinsically disordered proteins

VN Uversky - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2013 - Elsevier
Research of a past decade and a half leaves no doubt that complete understanding of
protein functionality requires close consideration of the fact that many functional proteins do …

A decade and a half of protein intrinsic disorder: biology still waits for physics

VN Uversky - Protein Science, 2013 - Wiley Online Library
The abundant existence of proteins and regions that possess specific functions without
being uniquely folded into unique 3D structures has become accepted by a significant …

Cis− trans isomerization of organic molecules and biomolecules: implications and applications

C Dugave, L Demange - Chemical reviews, 2003 - ACS Publications
Organic molecules as well as metal complexes may exist as several geometric isomers1
which display distinct physical properties and chemical reactivities. A molecule containing …

Structural basis of a phototropin light switch

SM Harper, LC Neil, KH Gardner - Science, 2003 - science.org
Phototropins are light-activated kinases important for plant responses to blue light. Light
initiates signaling in these proteins by generating a covalent protein–flavin mononucleotide …

The LOV domain family: photoresponsive signaling modules coupled to diverse output domains

S Crosson, S Rajagopal, K Moffat - Biochemistry, 2003 - ACS Publications
For single-cell and multicellular systems to survive, they must accurately sense and respond
to their cellular and extracellular environment. Light is a nearly ubiquitous environmental …

Conformational switching in the fungal light sensor Vivid

BD Zoltowski, C Schwerdtfeger, J Widom, JJ Loros… - Science, 2007 - science.org
The Neurospora crassa photoreceptor Vivid tunes blue-light responses and modulates
gating of the circadian clock. Crystal structures of dark-state and light-state Vivid reveal a …

Photoreceptor proteins,“star actors of modern times”: a review of the functional dynamics in the structure of representative members of six different photoreceptor …

MA Van Der Horst, KJ Hellingwerf - Accounts of chemical …, 2004 - ACS Publications
Six well-characterized photoreceptor families function in Nature to mediate light-induced
signal transduction: the rhodopsins, phytochromes, xanthopsins, cryptochromes …

Intrinsically disordered proteins play diverse roles in cell signaling

SE Bondos, AK Dunker, VN Uversky - Cell Communication and Signaling, 2022 - Springer
Signaling pathways allow cells to detect and respond to a wide variety of chemical (eg Ca2+
or chemokine proteins) and physical stimuli (eg, sheer stress, light). Together, these …

A photoactive carotenoid protein acting as light intensity sensor

A Wilson, C Punginelli, A Gall… - Proceedings of the …, 2008 - National Acad Sciences
Intense sunlight is dangerous for photosynthetic organisms. Cyanobacteria, like plants,
protect themselves from light-induced stress by dissipating excess absorbed energy as heat …

[КНИГА][B] 4D electron microscopy: imaging in space and time

AH Zewail, JM Thomas - 2009 - books.google.com
The modern electron microscope, as a result of recent revolutionary developments and
many evolutionary ones, now yields a wealth of quantitative knowledge pertaining to …