The field of stem-cell biology has been catapulted forward by the startling development of
reprogramming technology. The ability to restore pluripotency to somatic cells through the …

The human umbilical cord that originates from the embryo is an extra-embryonic membrane
and the Wharton's jelly within it is a rich source of stem cells (hWJSCs). It is not definitely …

Pluripotency pertains to the cells of early embryos that can generate all of the tissues in the
organism. Embryonic stem cells are embryo-derived cell lines that retain pluripotency and …

Tissue culture of immortal cell strains from diseased patients is an invaluable resource for
medical research but is largely limited to tumor cell lines or transformed derivatives of native …

Human dermal fibroblasts obtained by skin biopsy can be reprogrammed directly to
pluripotency by the ectopic expression of defined transcription factors. Here, we describe the …

The mammary gland undergoes significant remodeling during pregnancy and lactation,
which is fuelled by controlled mammary stem cell (MaSC) proliferation. The scarcity of …

Human embryonic stem cells (HESCs) are the in vitro descendants of the pluripotent inner
cell mass (ICM) of human blastocyst stage embryos. HESCs can be kept undifferentiated in …

Human induced pluripotent stem cells (iPSCs) derived from somatic cells of patients hold
great promise for modeling human diseases. Dermal fibroblasts are frequently used for …

Current approaches to reprogram human somatic cells to pluripotent iPSCs utilize viral
transduction of different combinations of transcription factors. These protocols are highly …

Breast milk contains bioactive molecules that provide a multitude of immunologic,
developmental and nutritional benefits to the infant. Less attention has been placed on the …