Targeting inflammation for the treatment of Diabetic Kidney Disease: A five-compartment mechanistic model

A Hofherr, J Williams, LM Gan, M Söderberg… - BMC nephrology, 2022 - Springer
Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide. Mortality
and morbidity associated with DKD are increasing with the global prevalence of type 2 …

Immunomodulator FTY720 improves glucose homeostasis and diabetic complications by rejuvenation of β‐cell function in nonhuman primate model of diabetes

Y Wang, X Wang, A An, M Zang, L Xu… - Fundamental & …, 2022 - Wiley Online Library
Inadequate β‐cell mass is essential for the pathogenesis of type 2 diabetes (T2D). Previous
report showed that an immunomodulator FTY720, a sphingosine 1‐phosphate (S1P) …

Imaging characterization of myocardial function, fibrosis, and perfusion in a nonhuman primate model with heart failure-like features

XL Liu, GZ Wang, MP Rui, D Fan, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction The availability of a human-like chronic heart failure (HF) animal model was
critical for affiliating development of novel therapeutic drug treatments. With the close …

Development, refinement, and characterization of a nonhuman primate critical care environment

JD Bozzay, PF Walker, RE Atwood, RW DeSpain… - Plos one, 2023 - journals.plos.org
Background Systemic inflammatory response remains a poorly understood cause of
morbidity and mortality after traumatic injury. Recent nonhuman primate (NHP) trauma …

[HTML][HTML] Низшие обезьяны как модельный объект изучения метаболического синдрома

СВ Орлов, ЮП Успенский, ЮА Фоминых… - Бюллетень …, 2024 - cyberleninka.ru
Цель работы–обобщение результатов исследований по изучению метаболического
синдрома на низших обезьянах, проведение сравнительной характеристики с …

Diagnostic and prognostic value of β2-microglobulin in the development of cardiorenal syndrome in patients with type 2 diabetes mellitus and arterial hypertension

I Dunaieva, O Bilovol - Problems of Endocrine Pathology, 2023 - ojs.endocrinology.org.ua
Arterial hypertension is the largest pandemic in the history of mankind, which defines the
structure of cardiovascular morbidity and mortality. Currently, the correlation between …

БЮЛЛЕТЕНЬ СИБИРСКОЙ МЕДИЦИНЫ

СВ ОРЛОВ, ЮП УСПЕНСКИЙ… - БЮЛЛЕТЕНЬ …, 2024 - elibrary.ru
Цель работы-обобщение результатов исследований по изучению метаболического
синдрома на низших обезьянах, проведение сравнительной характеристики с …

Immunomodulator FTY720 Rejuvenates β-cell and Ameliorates Cardiorenal Complications in Nonhuman Primate Model of Diabetes

YJ Wang, X Wang, A An, M Zang, L Xu, K Gong… - 2021 - researchsquare.com
Inadequate β-cell mass is essential for the pathogenesis of type 2 diabetes (T2D). Previous
report showed that an immunomodulator FTY720, a sphingosine 1-phosphate (S1P) …