Background Direct drug provocation test (DPT) without prior skin testing (ST) has been
investigated in children suspected of being at risk for beta-lactam (BL) hypersensitivity …

The burden of emerging antimicrobial resistance (AMR) in the United States is significant
and even greater worldwide. Mitigation efforts have decreased the incidence and deaths …

Background Penicillins (PCNs) are a first-line treatment option for bacterial pneumonia. PCN
allergy label can delay antimicrobial treatment and result in the use of alternative antibiotic …

Tuberculosis (TB) is the commonest cause of death by a single infectious agent globally and
ranks amongst the top ten causes of global mortality. The incidence of TB is highest in Low …

Abstract Purpose of Review To provide a review of available literature regarding
nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity with an emphasis on more …

Background The consequences of drug allergy remain a global health concern. Drug allergy
is often a neglected topic and many non‐specialists lack sufficient knowledge or confidence …

Background Penicillin allergy is the most commonly reported drug allergy in the US. Despite
evidence demonstrating that up to 90% of labels are incorrect, scalable interventions are not …

Although existing as a safety measure to prevent iatrogenic harm, unconfirmed penicillin
allergy labels have a negative impact on personal and public health. One downstream effect …

Inpatient direct oral challenge programs are increasingly deployed as part of antimicrobial
stewardship initiatives to reduce the burden and impacts of penicillin allergy labels on …

Background There is currently no standardized duration of drug provocation test (DPT) for
confirming/delabeling beta-lactam hypersensitivity reaction (BL-HSR). Objectives This meta …