Osteoblasts are integral to the development, growth, function, repair and maintenance of
bone. The osteoblast forms organic, non-mineralized bone matrix and is involved in complex …

Several congenital disorders can cause end stage bladder disease and possibly renal
damage in children. The current gold standard therapy is enterocystoplasty, a bladder …

Background MicroRNAs (miRNAs) are important regulators of gene expression, with
documented roles in bone metabolism and osteoporosis, suggesting potential therapeutic …

Osteogenetic microenvironment is a complex constitution in which extracellular matrix
(ECM) molecules, stem cells and growth factors each interact to direct the coordinate …

Bone grafts are the second most transplanted materials worldwide at a global cost to
healthcare systems valued over $30 billion every year. The influence of microRNAs in the …

Abstract microRNAs offer vast therapeutic potential for multiple disciplines. From a bone
perspective, inhibition of miR-133a may offer potential to enhance Runx2 activity and …

Bone regeneration is a coordinated process mainly regulated by multiple growth factors.
Vascular endothelial growth factor (VEGF) stimulates angiogenesis and bone …

Cyclical stretch‐induced bone formation during orthodontic treatment is a complex biological
process modulated by various factors including miRNAs and their targeted‐gene network …

Osteoblasts are specialized mesenchyme-derived cells accountable for bone synthesis,
remodelling and healing. Differentiation of osteoblasts from mesenchymal stem cells (MSC) …

Emerging evidence indicates that many microRNAs (miRNAs) are indispensable regulators
of osteoblast differentiation and bone formation. However, the role of miRNAs in …