Impairment of the blood–brain barrier (BBB) integrity is implicated in the numerous
neurological disorders associated with neuroinflammation, neurodegeneration and aging. It …

Despite a clear correlation between the infiltration of periodontal pathogens in the brain and
cognitive decline in Alzheimer's disease (AD), the precise mechanism underlying bacteria …

Stroke is the leading cause of global mortality and disability. Cerebral edema and
intracranial hypertension are common complications of cerebral infarction and the major …

Background The secondary injury caused by traumatic brain injury (TBI), especially white
matter injury (WMI), is highly sensitive to neuroinflammation, which further leads to …

Clostridium butyricum (CB) can enhance antioxidant capacity and alleviate oxidative
damage, but the molecular mechanism by which this occurs remains unclear. This study …

Cerebral ischemia/reperfusion (I/R) results in harmful consequences during ischemic stroke,
especially the disruption of the blood–brain barrier (BBB), which leads to severe …

The blood-testicular barrier (BTB) is involved in spermatogenesis, protects sperm
development, and plays a crucial role in the reproductive process. Tight junctions (TJs) …

The blood‑brain barrier (BBB) is critical for proper cerebral homeostasis and its dysfunction
during ischemic stroke can result in significant neurological injury. The major goal of the …

Short chain fatty acids (SCFAs) are known to be actively involved in multiple brain disorders,
but their roles in sepsis-associated encephalopathy (SAE) remain unclear. Here, we …

Intracerebral hemorrhage is the most dangerous complication in tPA thrombolytic therapy for
ischemic stroke, which occurs as a consequence of endothelial cell death at the blood–brain …