Curcumin and its derivatives as potential antimalarial and anti-inflammatory agents: a review on structure–activity relationship and mechanism of action

SNH Jamil, AH Ali, SR Feroz, SD Lam, HK Agustar… - Pharmaceuticals, 2023 - mdpi.com
Curcumin, one of the major ingredients of turmeric (Curcuma longa), has been widely
reported for its diverse bioactivities, including against malaria and inflammatory-related …

New opportunities and perspectives on biosynthesis and bioactivities of secondary metabolites from Aloe vera

MV Ushasree, Q Jia, SG Do, EY Lee - Biotechnology Advances, 2024 - Elsevier
Historically, the genus Aloe has been an indispensable part of both traditional and modern
medicine. Decades of intensive research have unveiled the major bioactive secondary …

Design and synthesis of novel glycyrrhetinic acid-triazole derivatives that exert anti-plasmodial activity inducing mitochondrial-dependent apoptosis in Plasmodium …

DS Kapkoti, S Kumar, A Kumar, MP Darokar… - New Journal of …, 2023 - pubs.rsc.org
Malaria is an enormous threat to public health due to the emergence of Plasmodium
falciparum resistance to widely used anti-malarials, such as chloroquine. Additionally, the …

Analysis of novel food proteins from plants

P Habibi, I Khan, S Venkataraman, M Faija… - Proteomics applied to …, 2024 - Springer
In the past decades, significant advancement has been made in plant-based platforms for
vaccine and pharmaceutical production. Various plant species, including tobacco, corn …

Senna occidentalis (L.) Link root extract inhibits Plasmodium growth in vitro and in mice

S Mogaka, H Molu, E Kagasi, K Ogila… - … Medicine and Therapies, 2023 - Springer
Abstract Background Senna occidentalis (L.) Link has been used worldwide in traditional
treatment of many diseases and conditions including snakebite. In Kenya, a decoction from …

[PDF][PDF] Evaluation of Antimalarial Activity of Combination Extract of Citrus aurantifolia and Honey against Plasmodium berghei-İnfected Mice.

DAAS Laksemi, IK Tunas, PAA Damayanti… - Tropical Journal of …, 2023 - researchgate.net
Previous studies have reported artemisinin resistance. Drugs for malaria treatment have
been developed from plants. Citrus aurantifolia was traditionally used to treat ailments. This …

Assessment of antimalarial activity of crude extract of Chan-Ta-Lee-La and Pra-Sa-Chan-Dang formulations and their plant ingredients for new drug candidates of …

P Chaniad, A Phuwajaroanpong, W Plirat, A Konyanee… - Plos one, 2024 - journals.plos.org
The emergence and spread of antimalarial drug resistance have become a significant
problem worldwide. The search for natural products to develop novel antimalarial drugs is …

Analysis of complementarities between nanomedicine and phytodrugs for the treatment of malarial infection

F Fulgheri, ML Manca, X Fernàndez-Busquets… - …, 2023 - Taylor & Francis
The use of nanocarriers in medicine, so-called nanomedicine, is one of the most innovative
strategies for targeting drugs at the action site and increasing their activity index and …

Recent advances in expression and purification strategies for plant made vaccines

S Venkataraman, I Khan, P Habibi, M Le… - Frontiers in Plant …, 2023 - frontiersin.org
Plants have been explored as a platform to produce pharmaceutical proteins for over 20
years. Important features such as the cost-effectiveness of production, the ease of scaling up …

Phytochemical evaluation of Ziziphus mucronata and Xysmalobium undulutum towards the discovery and development of anti-malarial drugs

MN Buthelezi, VG Tshililo, AP Kappo, MBC Simelane - Malaria Journal, 2024 - Springer
Background The development of resistance by Plasmodium falciparum is a burdening
hazard that continues to undermine the strides made to alleviate malaria. As such, there is …