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Sequencing-based methods and resources to study antimicrobial resistance
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
Using genomics to track global antimicrobial resistance
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
ResFinder–an open online resource for identification of antimicrobial resistance genes in next-generation sequencing data and prediction of phenotypes from …
Antimicrobial resistance (AMR) is one of the most important health threats globally. The
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …
ability to accurately identify resistant bacterial isolates and the individual antimicrobial …
Rapid expansion and international spread of M1UK in the post-pandemic UK upsurge of Streptococcus pyogenes
The UK observed a marked increase in scarlet fever and invasive group A streptococcal
infection in 2022 with severe outcomes in children and similar trends worldwide. Here we …
infection in 2022 with severe outcomes in children and similar trends worldwide. Here we …
Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low-and middle-income countries
Antimicrobial resistance in neonatal sepsis is rising, yet mechanisms of resistance that often
spread between species via mobile genetic elements, ultimately limiting treatments in low …
spread between species via mobile genetic elements, ultimately limiting treatments in low …
Rapid and precise alignment of raw reads against redundant databases with KMA
Background As the cost of sequencing has declined, clinical diagnostics based on next
generation sequencing (NGS) have become reality. Diagnostics based on sequencing will …
generation sequencing (NGS) have become reality. Diagnostics based on sequencing will …
Open-access bacterial population genomics: BIGSdb software, the PubMLST. org website and their applications
The PubMLST. org website hosts a collection of open-access, curated databases that
integrate population sequence data with provenance and phenotype information for over …
integrate population sequence data with provenance and phenotype information for over …
Completing bacterial genome assemblies with multiplex MinION sequencing
Illumina sequencing platforms have enabled widespread bacterial whole genome
sequencing. While Illumina data is appropriate for many analyses, its short read length limits …
sequencing. While Illumina data is appropriate for many analyses, its short read length limits …
ARIBA: rapid antimicrobial resistance genoty** directly from sequencing reads
Antimicrobial resistance (AMR) is one of the major threats to human and animal health
worldwide, yet few high-throughput tools exist to analyse and predict the resistance of a …
worldwide, yet few high-throughput tools exist to analyse and predict the resistance of a …
Staphylococcal diversity in atopic dermatitis from an individual to a global scale
Atopic dermatitis (AD) is a multifactorial, chronic relapsing disease associated with genetic
and environmental factors. Among skin microbes, Staphylococcus aureus and …
and environmental factors. Among skin microbes, Staphylococcus aureus and …