Antigen recognition detains CD8+ T cells at the blood-brain barrier and contributes to its breakdown
S Aydin, J Pareja, VM Schallenberg, A Klopstein… - Nature …, 2023 - nature.com
Blood-brain barrier (BBB) breakdown and immune cell infiltration into the central nervous
system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8+ T cells …
system (CNS) are early hallmarks of multiple sclerosis (MS). High numbers of CD8+ T cells …
Brain endothelial cells exposure to malaria parasites links type I interferon signalling to antigen presentation, immunoproteasome activation, endothelium disruption …
Introduction Cerebral malaria (CM) lethality is attributable to induction of brain edema
induction but the cellular mechanisms involving brain microvascular endothelium in CM …
induction but the cellular mechanisms involving brain microvascular endothelium in CM …
IQGAP2 regulates blood-brain barrier immune dynamics
Brain endothelial cells (BECs) play an important role in maintaining central nervous system
(CNS) homeostasis through blood-brain barrier (BBB) functions. BECs express low baseline …
(CNS) homeostasis through blood-brain barrier (BBB) functions. BECs express low baseline …
Elucidating Blood-Brain Barrier-mediated Mechanisms of Central Nervous System Immune Privilege
KA Katdare - 2023 - search.proquest.com
Central nervous system (CNS) immune privilege is imparted by a complex set of
mechanisms designed to protect the fragile brain tissue. Brain endothelial cells (BECs), the …
mechanisms designed to protect the fragile brain tissue. Brain endothelial cells (BECs), the …