An antibody-drug conjugate (ADC) provides the possibility of selectively ablating cancer
cells by combining the specificity of a monoclonal antibody (mAb) for a target antigen with …

The burgeoning field of anaplastic lymphoma kinase (ALK) in cancer encompasses many
cancer types, from very rare cancers to the more prevalent non-small-cell lung cancer …

Now available in a thoroughly revised Twelfth Edition, Wintrobe's Clinical Hematology
continues to be an industry leader with its ability to correlate basic science with the clinical …

Tyrosine kinases are involved in the pathogenesis of most cancers. However, few tyrosine
kinases have been shown to have a well-defined pathogenetic role in lymphomas. The …

Background: The first silicone breast implant was inserted in 1962. In 1997, the first case of
anaplastic large cell lymphoma (ALCL) in association with a silicone breast implant was …

The molecular alterations underlying the pathogenesis of angioimmunoblastic T-cell
lymphoma (AITL) and peripheral T-cell lymphoma, unspecified (PTCL-u) are largely …

Importance Breast implant–associated anaplastic large cell lymphoma (BIA-ALCL), a rare
peripheral T-cell lymphoma, is increasing in incidence. However, many practitioners who …

In the past 50 years, we have witnessed explosive growth in the understanding of normal
and neoplastic lymphoid cells. B-cell, T-cell, and natural killer (NK)–cell neoplasms in many …

RTKs (receptor tyrosine kinases) play important roles in cellular proliferation and
differentiation. In addition, RTKs reveal oncogenic potential when their kinase activities are …

Although significant improvements have been made in the outcomes of children with cancer,
the pace of improvement has slowed in recent years as the limits of therapy intensification …