Blood and lymphatic vessels pervade almost all body tissues and have numerous essential
roles in physiology and disease. The inner lining of these networks is formed by a single …

Cerebral cavernous malformations are acquired vascular anomalies that constitute a
common cause of central nervous system hemorrhage and stroke. The past 2 decades have …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

Capillary malformation (CM), or" port-wine stain," is a common cutaneous vascular anomaly
that initially appears as a red macular stain that darkens over years. CM also occurs in …

Hemorrhagic stroke comprises about 20% of all strokes, with intracerebral hemorrhage
(ICH) being the most common type. Frequency of ICH is increased where hypertension is …

The National Institute of Neurological Disorders and Stroke and the Office of Rare Disorders
sponsored a workshop on perinatal and childhood stroke in Bethesda, Maryland, on …

Background Hemangiomas of infancy vary widely in appearance, size, and depth of
cutaneous involvement. There is currently no standard classification system for these …

We previously mapped susceptibility to stroke to chromosome 5q12. Here we finely mapped
this locus and tested it for association with stroke. We found the strongest association in the …

The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …

Cerebral cavernous malformations (CCMs) are hamartomatous vascular malformations
characterized by abnormally enlarged capillary cavities without intervening brain …