[HTML][HTML] Bidirectional roles of skeletal muscle fibro-adipogenic progenitors in homeostasis and disease
Sarcopenia and myopathies cause progressive muscle weakness and degeneration, which
are closely associated with fat infiltration and fibrosis in muscle. Recently, experimental …
are closely associated with fat infiltration and fibrosis in muscle. Recently, experimental …
A glitch in the matrix: the pivotal role for extracellular matrix remodeling during muscle hypertrophy
Multinuclear muscle fibers are the most voluminous cells in skeletal muscle and the primary
drivers of growth in response to loading. Outside the muscle fiber, however, is a diversity of …
drivers of growth in response to loading. Outside the muscle fiber, however, is a diversity of …
Thrown for a loop: fibro-adipogenic progenitors in skeletal muscle fibrosis
Fibro-adipogenic progenitors (FAPs) are key regulators of skeletal muscle regeneration and
homeostasis. However, dysregulation of these cells leads to fibro-fatty infiltration across …
homeostasis. However, dysregulation of these cells leads to fibro-fatty infiltration across …
[HTML][HTML] Unlocking the potential of stem cells: Their crucial role in the production of cultivated meat
DK Lee, M Kim, J Jeong, YS Lee, JW Yoon… - Current Research in …, 2023 - Elsevier
Cellular agriculture is an emerging research field of agribiotechnology that aims to produce
agricultural products using stem cells, without sacrificing animals or cultivating crops …
agricultural products using stem cells, without sacrificing animals or cultivating crops …
Muscle fibro-adipogenic progenitors from a single-cell perspective: Focus on their “virtual” secretome
E Negroni, M Kondili, L Muraine, M Bensalah… - Frontiers in Cell and …, 2022 - frontiersin.org
Skeletal muscle is a highly plastic tissue composed of a number of heterogeneous cell
populations that, by interacting and communicating with each other, participate to the muscle …
populations that, by interacting and communicating with each other, participate to the muscle …
Radiation induces long‐term muscle fibrosis and promotes a fibrotic phenotype in fibro‐adipogenic progenitors
N Collao, D D'Souza, L Messeiller… - Journal of Cachexia …, 2023 - Wiley Online Library
Background Radiation‐induced muscle pathology, characterized by muscle atrophy and
fibrotic tissue accumulation, is the most common debilitating late effect of therapeutic …
fibrotic tissue accumulation, is the most common debilitating late effect of therapeutic …
[HTML][HTML] Single-cell RNA sequencing in skeletal muscle developmental biology
C Cai, Y Yue, B Yue - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Skeletal muscle is the most extensive tissue in mammals, and they perform several
functions; it is derived from paraxial mesodermal somites and undergoes hyperplasia and …
functions; it is derived from paraxial mesodermal somites and undergoes hyperplasia and …
MuSCs and IPCs: Roles in skeletal muscle homeostasis, aging and injury
H Jiang, B Liu, J Lin, T Xue, Y Han, C Lu… - Cellular and Molecular …, 2024 - Springer
Skeletal muscle is a highly specialized tissue composed of myofibres that performs crucial
functions in movement and metabolism. In response to external stimuli and injuries, a range …
functions in movement and metabolism. In response to external stimuli and injuries, a range …
[HTML][HTML] PPARγ agonist treatment reduces fibroadipose tissue in secondary lymphedema by exhausting fibroadipogenic PDGFRα+ mesenchymal cells
Secondary lymphedema occurs in up to 20% of patients after lymphadenectomy performed
for the surgical management of tumors involving the breast, prostate, uterus, and skin …
for the surgical management of tumors involving the breast, prostate, uterus, and skin …
Muscle denervation promotes functional interactions between glial and mesenchymal cells through NGFR and NGF
We performed scRNA-seq/snATAC-seq of skeletal muscles post sciatic nerve transection to
delineate cell type-specific patterns of gene expression/chromatin accessibility at different …
delineate cell type-specific patterns of gene expression/chromatin accessibility at different …