The etiopathogenesis of depression is not entirely understood. Several studies have
investigated the role of inflammation in major depressive disorder. The present work aims to …

Major depressive disorder (MDD) continues to impose a significant burden on individuals
and society. Existing data support the important role that inflammatory responses play in its …

Background About every fourth patient with major depressive disorder (MDD) shows
evidence of systemic inflammation. Previous studies have shown inflammation-depression …

Background Although there is scientific evidence of the presence of immunometabolic
alterations in major depression, not all patients present them. Recent studies point to the …

There is convergent evidence that the immune system is dysregulated in some depressed
individuals. A psychoneuroimmunology-based understanding of depression is advancing …

Background We aimed to clarify the controversial relationship between levels of high-
sensitivity C-reactive protein (hs-CRP) and severity of depression in men and women …

Adolescent depression is characterized by heightened inflammation and altered connectivity
of fronto-cingulate-limbic tracts, including the genu of the corpus callosum (CCG) and the …

Background Prioritizing the maintenance of healthy cognitive aging and personalizing
preventive interventions to enhance their effectiveness is crucial as the global population …

BackgroundVulnerability theories propose that suboptimal levels of lipid markers and
proinflammatory proteins predict future heightened depression. Scar models posit the …

Introduction Studies investigating the association between C-reactive protein (CRP) and
depression among older adults have yielded inconsistent results. We suspect that this may …