The OCT angular sign of Henle fiber layer (HFL) hyperreflectivity (ASHH) and the pathoanatomy of the HFL in macular disease

P Ramtohul, D Cabral, SV Sadda, KB Freund… - Progress in Retinal and …, 2023 - Elsevier
The Henle fiber layer (HFL) is comprised of bundles of unmyelinated photoreceptor axons
intermingled with outer Müller cell processes. The photoreceptor axons extend from the cell …

Non-Neovascular Age-Related Macular Degeneration Assessment: Focus on Optical Coherence Tomography Biomarkers

DA Iliescu, AC Ghita, LA Ilie, SE Voiculescu… - Diagnostics, 2024 - mdpi.com
The imagistic evaluation of non-neovascular age-related macular degeneration (AMD) is
crucial for diagnosis, monitoring progression, and guiding management of the disease. Dry …

Challenges associated with ellipsoid zone intensity measurements using optical coherence tomography

KE Lee, H Heitkotter, J Carroll - Translational vision science & …, 2021 - tvst.arvojournals.org
Optical coherence tomography (OCT) allows noninvasive visualization of individual retinal
layers and has become a mainstay in the diagnosis and management of a wide range of …

Beyond backscattering: optical neuroimaging by BRAD

P Eugui, A Lichtenegger, M Augustin… - Biomedical optics …, 2018 - opg.optica.org
Optical coherence tomography (OCT) is a powerful technology for rapid volumetric imaging
in biomedicine. The bright field imaging approach of conventional OCT systems is based on …

Three-dimensional structural and angiographic evaluation of foveal ischemia in diabetic retinopathy: method and validation

B Wang, A Camino, S Pi, Y Guo, J Wang… - Biomedical Optics …, 2019 - opg.optica.org
Optical coherence tomography angiography (OCTA) allows us to noninvasively investigate
foveal ischemia, a key feature of diabetic retinopathy (DR). However, the sizes of the foveal …

Using directional OCT to analyze photoreceptor visibility over AMD-related drusen

B Marsh-Armstrong, KS Murrell, D Valente… - Scientific reports, 2022 - nature.com
Investigators have reported reduced visibility of the cone photoreceptors overlying drusen
using adaptive optics (AO) imaging techniques. Two hypotheses have been proposed to …

Design considerations for murine retinal imaging using scattering angle resolved optical coherence tomography

MR Gardner, N Katta, AS Rahman, HG Rylander III… - Applied Sciences, 2018 - mdpi.com
Featured Application Scattering angle resolved optical coherence tomography offers a new
contrast mechanism for murine retinal imaging. Abstract Optical coherence tomography …

Scattering angle resolved optical coherence tomography detects early changes in 3xTg Alzheimer's disease mouse model

MR Gardner, V Baruah, G Vargas… - … Vision Science & …, 2020 - tvst.arvojournals.org
Purpose: Clinical intensity-based optical coherence tomographic retinal imaging is unable to
resolve some of the earliest changes to Alzheimer's disease (AD) neurons. The aim of this …

[HTML][HTML] Optical coherence tomography reveals light-dependent retinal responses in Alzheimer's disease

D Bissig, CG Zhou, V Le, JT Bernard - Neuroimage, 2020 - Elsevier
Spectral-domain optical coherence tomography (SD-OCT) is an accessible clinical tool for
measuring structural changes to the retina, and increasingly as a biomarker for brain …

Volumetric directional optical coherence tomography

S Ni, S Khan, TTP Nguyen, R Ng, BJ Lujan… - Biomedical Optics …, 2022 - opg.optica.org
Photoreceptor loss and resultant thinning of the outer nuclear layer (ONL) is an important
pathological feature of retinal degenerations and may serve as a useful imaging biomarker …