Clinical impact of computational heart valve models

M Toma, S Singh-Gryzbon, E Frankini, Z Wei… - Materials, 2022 - mdpi.com
This paper provides a review of engineering applications and computational methods used
to analyze the dynamics of heart valve closures in healthy and diseased states …

Endovascular ascending aortic repair in type A dissection: a systematic review

Y Ahmed, IB Houben, CA Figueroa… - Journal of cardiac …, 2021 - Wiley Online Library
Purpose Up to 10% of acute type A aortic dissection (TAAD) patients are deemed unfit for
open surgical repair, exposing these patients to high mortality rates. In recent years, thoracic …

CRIMSON: An open-source software framework for cardiovascular integrated modelling and simulation

CJ Arthurs, R Khlebnikov, A Melville… - PLoS computational …, 2021 - journals.plos.org
In this work, we describe the CRIMSON (CardiovasculaR Integrated Modelling and
SimulatiON) software environment. CRIMSON provides a powerful, customizable and user …

The importance of blood rheology in patient-specific computational fluid dynamics simulation of stenotic carotid arteries

JB Mendieta, D Fontanarosa, J Wang… - … and Modeling in …, 2020 - Springer
The initiation and progression of atherosclerosis, which is the main cause of cardiovascular
diseases, correlate with local haemodynamic factors such as wall shear stress (WSS) …

Impact of patient-specific inflow velocity profile on hemodynamics of the thoracic aorta

P Youssefi, A Gomez, C Arthurs… - Journal of …, 2018 - asmedigitalcollection.asme.org
Computational fluid dynamics (CFD) provides a noninvasive method to functionally assess
aortic hemodynamics. The thoracic aorta has an anatomically complex inlet comprising of …

Shear stress and aortic strain associations with biomarkers of ascending thoracic aortic aneurysm

S Pasta, V Agnese, A Gallo, F Cosentino… - The Annals of thoracic …, 2020 - Elsevier
Background This study aims to investigate the association of wall shear stress (WSS) and
aortic strain with circulating biomarkers including matrix metalloproteinases (MMP), tissue …

Application of computational fluid dynamics for detection of high risk region in middle cerebral artery (MCA) aneurysm

A Rostamian, K Fallah, Y Rostamiyan… - International Journal of …, 2023 - World Scientific
In the recent decades, the main reason for the high death rate is related to cardiovascular
disease and stroke. In this paper, numerical studies have been done to investigate the …

Role of ADAMTS-5 in aortic dilatation and extracellular matrix remodeling

M Fava, J Barallobre-Barreiro, U Mayr… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Thoracic aortic aneurysm (TAA), a degenerative disease of the aortic wall, is
accompanied by changes in the structure and composition of the aortic ECM (extracellular …

Computational fluid dynamic study for aTAA hemodynamics: an integrated image-based and radial basis functions mesh morphing approach

K Capellini, E Vignali, E Costa… - Journal of …, 2018 - asmedigitalcollection.asme.org
We present a novel framework for the fluid dynamics analysis of healthy subjects and
patients affected by ascending thoracic aorta aneurysm (aTAA). Our aim is to obtain …

Coupling hemodynamics with mechanobiology in patient-specific computational models of ascending thoracic aortic aneurysms

SJ Mousavi, R Jayendiran, S Farzaneh… - Computer Methods and …, 2021 - Elsevier
Abstract Background and Objective. The prevention of ascending thoracic aortic aneurysms
(ATAAs), which affect thousands of persons every year worldwide, remains a major issue …