Adrenal insufficiency (AI) is a condition characterized by an absolute or relative deficiency of
adrenal cortisol production. Primary AI (PAI) is rare and is caused by direct adrenal failure …

Adrenal insufficiency is the clinical manifestation of deficient production or action of
glucocorticoids, with or without deficiency also in mineralocorticoids and adrenal androgens …

Objective: To formulate clinical practice guidelines for hormonal replacement in
hypopituitarism in adults. Participants: The participants include an Endocrine Society …

Objective: The aim was to update The Endocrine Society Clinical Practice Guideline on
Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published …

Adrenal insufficiency is caused by either primary adrenal failure (mostly due to autoimmune
adrenalitis) or by hypothalamic-pituitary impairment of the corticotropic axis (predominantly …

Background Four retrospective studies have reported premature mortality in patients with
hypopituitarism with standard mortality ratios (SMRs) varying between 1· 20 and 2· 17 …

Adrenal crisis is a life-threatening emergency contributing to the excess mortality of patients
with adrenal insufficiency. Studies in patients on chronic replacement therapy for adrenal …

Chronic excessive activation of glucocorticoid receptors induces obesity, insulin resistance,
glucose intolerance, dyslipidaemia and hypertension. Subtle abnormalities of the …

Pituitary disease is associated with increased mortality predominantly due to vascular
disease. Control of cortisol secretion and GH hypersecretion (and cardiovascular risk factor …

Growth Hormone Deficiency in Adulthood and the Effects of Growth Hormone Replacement: A
Review | The Journal of Clinical Endocrinology & Metabolism | Oxford Academic Skip to Main …