The global burden of community-acquired pneumonia in adults, encompassing invasive pneumococcal disease and the prevalence of its associated cardiovascular …
R Anderson, C Feldman - International Journal of Molecular Sciences, 2023 - mdpi.com
Despite innovative advances in anti-infective therapies and vaccine development
technologies, community-acquired pneumonia (CAP) remains the most persistent cause of …
technologies, community-acquired pneumonia (CAP) remains the most persistent cause of …
Pangenome-spanning epistasis and coselection analysis via de Bruijn graphs
J Kuronen, ST Horsfield, AK Pöntinen… - Genome …, 2024 - genome.cshlp.org
Studies of bacterial adaptation and evolution are hampered by the difficulty of measuring
traits such as virulence, drug resistance, and transmissibility in large populations. In contrast …
traits such as virulence, drug resistance, and transmissibility in large populations. In contrast …
Extensive remodelling of the cell wall during the development of Staphylococcus aureus bacteraemia
The bloodstream represents a hostile environment that bacteria must overcome to cause
bacteraemia. To understand how the major human pathogen Staphylococcus aureus …
bacteraemia. To understand how the major human pathogen Staphylococcus aureus …
Seasonal Azithromycin use in paediatric protracted bacterial bronchitis does not promote antimicrobial resistance but does modulate the nasopharyngeal microbiome
SJ Hardman, FM Shackley, K Ugonna… - International Journal of …, 2023 - mdpi.com
Protracted bacterial bronchitis (PBB) causes chronic wet cough for which seasonal
azithromycin is increasingly used to reduce exacerbations. We investigated the impact of …
azithromycin is increasingly used to reduce exacerbations. We investigated the impact of …
High-throughput mutagenesis reveals a role for antimicrobial resistance-and virulence-associated mobile genetic elements in Staphylococcus aureus host adaptation
Methicillin-resistant Staphylococcus aureus (MRSA) clonal-complex 398 (CC398) is the
dominant livestock-associated (LA) MRSA lineage in European livestock and an increasing …
dominant livestock-associated (LA) MRSA lineage in European livestock and an increasing …
A 3'UTR-derived small RNA represses pneumolysin synthesis and facilitates pneumococcal brain invasion
K Shen, W Miao, L Zhu, Q Hu, F Ren, X Dong… - Communications …, 2024 - nature.com
Abstract Pneumolysin (Ply) of Streptococcus pneumoniae (pneumococcus) at relatively high
and low levels facilitates pneumococcal invasion into the lung and brain, respectively; …
and low levels facilitates pneumococcal invasion into the lung and brain, respectively; …
PAN-GWES: Pangenome-spanning epistasis and co-selection analysis via de Bruijn graphs
J Kuronen, S Horsfield, AK Pöntinen… - bioRxiv, 2023 - biorxiv.org
Studies of bacterial adaptation and evolution are hampered by the difficulty of measuring
traits such as virulence, drug resistance and transmissibility in large populations. In contrast …
traits such as virulence, drug resistance and transmissibility in large populations. In contrast …
[PDF][PDF] Review Not peer-reviewed version
R Anderson, C Feldman - 2023 - preprints.org
Despite innovative advances in anti-infective therapies and vaccine development
technologies, community-acquired pneumonia (CAP) remains the most persistent cause of …
technologies, community-acquired pneumonia (CAP) remains the most persistent cause of …
Self-sensitisation of Staphylococcus aureus to the antimicrobial factors found in human blood
Introductory Paragraph For opportunistic pathogens, the switch from a commensal to an
invasive lifestyle is often considered an accidental event. But with plentiful opportunity, what …
invasive lifestyle is often considered an accidental event. But with plentiful opportunity, what …