[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Designing antibodies as therapeutics

PJ Carter, A Rajpal - Cell, 2022 - cell.com
Antibody therapeutics are a large and rapidly expanding drug class providing major health
benefits. We provide a snapshot of current antibody therapeutics including their formats …

Mechanisms of nanoparticle transport across intestinal tissue: an oral delivery perspective

SA Ejazi, R Louisthelmy, K Maisel - ACS nano, 2023 - ACS Publications
Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …

[HTML][HTML] Ionotropic gelation and chemical crosslinking as methods for fabrication of modified-release gellan gum-based drug delivery systems

P Gadziński, A Froelich, B Jadach, M Wojtyłko… - Pharmaceutics, 2023 - mdpi.com
Hydrogels have a tridimensional structure. They have the ability to absorb a significant
amount of water or other natural or simulated fluids that cause their swelling albeit without …

An overview of nanostructured lipid carriers and its application in drug delivery through different routes

S Khan, A Sharma, V Jain - Advanced pharmaceutical bulletin, 2022 - pmc.ncbi.nlm.nih.gov
Nanostructured Lipid Carriers (NLC) are nano-sized colloidal drug delivery system that
contains a lipid mixture consisting of both solid and liquid lipids in their core. This Lipid …

[HTML][HTML] Advancements, challenges and future perspectives on peptide-based drugs: Focus on antimicrobial peptides

X Luo, H Chen, Y Song, Z Qin, L Xu, N He, Y Tan… - European Journal of …, 2023 - Elsevier
Among other health related issues, the rising concerns on drug resistance led to look for
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …

Strategic approaches to improvise peptide drugs as next generation therapeutics

P Barman, S Joshi, S Sharma, S Preet… - International journal of …, 2023 - Springer
In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

A novel angiotensin-converting enzyme (ACE) inhibitory peptide from tilapia skin: Preparation, identification and its potential antihypertensive mechanism

Y Dong, W Yan, YQ Zhang, ZY Dai - Food Chemistry, 2024 - Elsevier
To obtain food-derived peptides with high ACE inhibitory activity, tilapia skin was pretreated
with steam explosion prior to enzymatic hydrolysis. The results showed that steam explosion …

Milk exosome–liposome hybrid vesicles with self-adapting surface properties overcome the sequential absorption barriers for oral delivery of peptides

P **ao, H Wang, H Liu, H Yuan, C Guo, Y Feng, P Qi… - ACS …, 2024 - ACS Publications
Milk exosomes (mExos) have demonstrated significant promise as vehicles for the oral
administration of protein and peptide drugs owing to their superior capacity to traverse …

Calcium phosphate-based nanomaterials: preparation, multifunction, and application for bone tissue engineering

X Chen, H Li, Y Ma, Y Jiang - Molecules, 2023 - mdpi.com
Calcium phosphate is the main inorganic component of bone. Calcium phosphate-based
biomaterials have demonstrated great potential in bone tissue engineering due to their …