Microsatellite instability: from the implementation of the detection to a prognostic and predictive role in cancers
Microsatellite instability (MSI) has been identified in several tumors arising from either
germline or somatic aberration. The presence of MSI in cancer predicts the sensitivity to …
germline or somatic aberration. The presence of MSI in cancer predicts the sensitivity to …
MLH1 Methylation Testing as an Integral Component of Universal Endometrial Cancer Screening—A Critical Appraisal
Simple Summary Often in endometrial cancer (EC), the mismatch repair (MMR) system,
which helps fix DNA mistakes, goes haywire because of MLH1 promoter hypermethylation …
which helps fix DNA mistakes, goes haywire because of MLH1 promoter hypermethylation …
Case report: Exploring Lynch Syndrome through genomic analysis in a mestizo Ecuadorian patient and his brother
Lynch Syndrome (LS) is a hereditary disorder characterized by genetic mutations in DNA
mismatch repair genes, affecting approximately 0.35% of the population. LS primarily …
mismatch repair genes, affecting approximately 0.35% of the population. LS primarily …
Immunohistochemical Markers in Endometrial Cancer: Latest Updates
V Mais, M Peiretti - Cancers, 2023 - mdpi.com
Ten years ago, The Cancer Genome Atlas (TGCA) Research Network classified endometrial
cancer into four molecular categories with prognostic significance, suggesting sensitivity to …
cancer into four molecular categories with prognostic significance, suggesting sensitivity to …
[HTML][HTML] Correlation between immunohistochemical staining and clinicopathological findings in endometrial carcinoma
SN Saharti, FJ Altaf - Saudi Medical Journal, 2024 - ncbi.nlm.nih.gov
Objectives: To analyze the immunohistochemical staining pattern of mismatch repair (MMR)
proteins and p53 in endometrial carcinoma cases, including different subtypes and stages …
proteins and p53 in endometrial carcinoma cases, including different subtypes and stages …
[PDF][PDF] The Role of Epigenetics in Hereditary Colorectal Cancer Tumorigenesis: Validation of Genome
T Puustinen - Nature Reviews Clinical Oncology, 2022 - helda.helsinki.fi
Colorectal cancer (CRC) poses a considerable global health challenge, with high mortality
rates despite advancements in cancer research. Approximately one in ten CRC cases have …
rates despite advancements in cancer research. Approximately one in ten CRC cases have …